Abstract
Maternal smoking is known to be one of the SIDS risk factors1. With maternal smoking, nicotine is transported through the placenta to a fetus, and nicotine concentration fluctuates in fetal blood2,3. Also smoking of a mother makes nicotine concentration fluctuates in infantile blood through breast milk or cigarette smoke4,5 Because nicotine has been known to stimulate respiratory neuronal network in the brainstem6,7, fluctuation in the fetal or infantile blood nicotine concentration may induce instability of fetal respiration-like activity or infantile respiratory activity, and may be related to the pathophysiology of SIDS.
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Okada, Y., Kuwana, Si., Iwanami, M. (2001). Respiratory Suppression Induced by Nicotine Withdrawal in the Neonatal Rat Brainstem. In: Poon, CS., Kazemi, H. (eds) Frontiers in Modeling and Control of Breathing. Advances in Experimental Medicine and Biology, vol 499. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1375-9_29
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DOI: https://doi.org/10.1007/978-1-4615-1375-9_29
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