Respiratory Control of Hypoglossal Motoneurons
Hypoglossal motoneurons innervate the tongue muscles1which participate in a variety of motor tasks, including breathing.2Understanding the respiratory control of hypoglossal motoneurons is essential because of their critical involvement in maintaining airway patency during normal breathing, and their putative role in the pathogenesis of obstructive sleep apnea.3, 4Despite such importance in both normal and altered physiological states, virtually nothing is known about how respiratory rhythm is transmitted to them.
KeywordsObstructive Sleep Apnea Hypoglossal Nerve Respiratory Rhythm Hypoglossal Nucleus Premotor Neuron
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