Abstract
We evaluated several reports on the detection of nitromusks (artificial perfumes) in human milk The nitromusks found were separated by gas-liquid chromatography and identified by mass spectrometry. However, the quantities reported as being consumed by infants were often questionable (Jensen, 1995). The investigators did not always a) obtain a representative samples of milk, b) extract and quantify the fat by a recognized, accurate method, or c) determine the amount of milk, hence fat, consumed by the infant. Some investigators gave almost no data on the milk, except to say that a sample was obtained. Reports on some other contaminants in human milk were similarly deficient. We have published a description of recommended extraction procedures in a paper presenting a detailed protocol for the processing of milk so as to determine the actual amounts of lipophilic contaminants ingested by the nursing infant (Jensen et al. 1997).
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References
Jensen RG. Comments on the extraction of fat from human milk for analysis of contaminants [letter]. Chemosphere 1995;31:4197–4205.
Jensen RG, Lammi-Keefe CJ, KoletzkoB. Representative sampling of human milk and the extraction of fat for analysis of environmental lipophilic contaminants. Toxicol Environ Chem 1997;62:229–247.
Quinsey DM, Donohue DC, Cumming FJ, Ahokas JT. The importance of measured intake in assessing exposure of breast-fed infants to organochlorines. Eur J Clin Nutr 1996;50:438–442.
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© 2001 Springer Science+Business Media New York
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Jensen, R.G., Lammi-Keefe, C.J., Koletzko, B. (2001). Consumption of Lipophilic Contaminants in Human Milk by Infants. In: Newburg, D.S. (eds) Bioactive Components of Human Milk. Advances in Experimental Medicine and Biology, vol 501. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1371-1_67
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DOI: https://doi.org/10.1007/978-1-4615-1371-1_67
Publisher Name: Springer, Boston, MA
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