Abstract
Long-chain polyunsaturated fatty acids (LC-PUFA) accretion (essential for growth and neural development) was studied from late fetal throughout weaning age in the ferret, a species with maternal LC-PUFA sufficiency during pregnancy and lactation. The data show that a) accretion rate of LC-PUFA is rapid during early postnatal development, b) milk LC-PUFA decrease during lactation, c) adipose tissur, LC-PUFA level is directly related to milk LC-PUFA level, while accretion in brair and liver exceeds dietary intake, d) accretion of arachidonic acid occurs earlier than docosahexaenoic acid, suggesting earlier development of n6-fatty acid endogenous synthesis.
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© 2001 Springer Science+Business Media New York
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Hamosh, M., Henderson, T.R., Kemper, M.A., Orr, N.M., Gil, A., Hamosh, P. (2001). Long-Chain Polyunsaturated Fatty Acids (LC-PUFA) During Early Development. In: Newburg, D.S. (eds) Bioactive Components of Human Milk. Advances in Experimental Medicine and Biology, vol 501. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1371-1_49
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DOI: https://doi.org/10.1007/978-1-4615-1371-1_49
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