The Anticarcinogenic Conjugated Fatty Acid c9, t11-C18:2, or Rumenic Acid, in Human Milk

Amounts and Effects
  • Robert G. Jensen
  • Carol Lammi-Keefe
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 501)


The conjugated linoleic acid (CLA) c9, tl1-C18:2 has been detected in human milk by gas-liquid chromotography (GLC) using standards for tentative identification. The amounts found were: 5.5 mg/g fat, Australia, 1988; and 3.6 mg/g fat, Idaho, 1997. We also employed GLC and standards and confirmed the identity of coeluting peaks by mass spectrometry. Our values were 1.8 ± 0.02 mg/g fat. CLA inhibits growth of several cancers, is antiatherosclerotic, partially overcomes catabolic responses to endotoxin injection, enhances weight gain and improves feed efficiency in rats, and modulates immune response and bone deposition. The dietary sources are ruminant-derived foods, particularly aged cheese.


Linoleic Acid Conjugated Linoleic Acid Human Milk Bovine Milk Cheddar Cheese 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Robert G. Jensen
    • 1
  • Carol Lammi-Keefe
    • 1
  1. 1.Department of Nutritional SciencesUniversity of ConnecticutStorrsUSA

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