Neuroprotective Strategies in Epilepsy

  • Peter L. Carlen
  • Marc R. Pelletier
  • Aviv Ouanounou
  • Michael Tymianski
  • Liang Zhang
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 497)


It is well known that brain damage can cause epilepsy. Post-traumatic epilepsy (PTE), for instance, is a consequence of traumatic brain injury. The risk of PTE ranges from less than 5 percent of patients following blunt head trauma (e.g., simple skull fracture) to 50 percent in patients following penetrating wounds or those involving intracranial hematoma.11 One of the accepted causes of temporal-lobe epilepsy is perinatal brain injury, which can also lead to other epileptic syndromes, such as West’s syndrome and Lennox-Gastaut syndrome. Epilepsy can also be a presenting symptom of both brain tumors and strokes.


Nerve Growth Factor Status Epilepticus Metabotropic Glutamate Receptor Kainic Acid Brain Damage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2000

Authors and Affiliations

  • Peter L. Carlen
    • 1
  • Marc R. Pelletier
    • 1
  • Aviv Ouanounou
    • 1
  • Michael Tymianski
    • 1
  • Liang Zhang
    • 1
  1. 1.The Toronto Western HospitalTorontoCanada

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