Antioxidants, Free Radical Stress and Diabetes

  • Shanti S. Rastogi
  • Ram B. Singh
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 498)

Abstract

The DCCT, the UKPD and the DAGMI studies have demonstrated the role of hypoglycemic agents such as human insulin and metformin in the management of diabetes and its vascular complications and in decreasing mortality. However, many subjects died in the intervention groups of these studies indicating that beyond tight control of glucose, further intervention is necessary to reduce clinical events and progression of vascular disease. Increased consumption of refined sugar, total and saturated fat and linoleic acid rich oils and lower intake of n-3 fatty acids and antioxidant vitamins and coenzyme Q10 in the diet in association with smoking and sedentaryness have been suggested to be important risk factors of diabetes and cardiovascular disease (CVD)1–3

Keywords

Cholesterol Zinc Obesity Peroxide Glutathione 

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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Shanti S. Rastogi
    • 1
  • Ram B. Singh
    • 2
  1. 1.Endocrine Point and Centre for Diabetes and NutritionDelhiIndia
  2. 2.Medical Hospital and Research CentreMoradabadIndia

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