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Endothelial Integrity and Repair

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Diabetes and Cardiovascular Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 498))

Abstract

Large artery endothelial integrity and repair is an important area of investigation in atherosclerosis research. The development of an atherosclerotic plaque (fibrofatty plaque) is a dynamic and complex process that is closely associated with the structure and dysfunction of endothelial cells. Although the sequence of events that lead to the initiation and growth of fibrofatty atherosclerotic plaques is not well understood, there is much experimental and clinical support for the concept that disruption of structural and functional endothelial integrity plays an important role in atherogenesis.

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Author information

Authors and Affiliations

  1. Toronto General Hospital, 200 Elizabeth Street CCRW 1-857, Toronto, Ontario, M5G 2C4

    Tsu-Yee Joseph Lee, Sabrena Noria, Joanne Lee & Avrum I. Gotlieb

Authors
  1. Tsu-Yee Joseph Lee
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  2. Sabrena Noria
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  3. Joanne Lee
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  4. Avrum I. Gotlieb
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Editor information

Editors and Affiliations

  1. Diabetes Research and Treatment Centre, Winnipeg, Canada

    Aubie Angel

  2. St. Boniface Research Centre, Winnipeg, Canada

    Naranjan Dhalla , Grant Pierce  & Pawan Singal ,  & 

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© 2001 Springer Science+Business Media New York

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Lee, TY.J., Noria, S., Lee, J., Gotlieb, A.I. (2001). Endothelial Integrity and Repair. In: Angel, A., Dhalla, N., Pierce, G., Singal, P. (eds) Diabetes and Cardiovascular Disease. Advances in Experimental Medicine and Biology, vol 498. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1321-6_10

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  • DOI: https://doi.org/10.1007/978-1-4615-1321-6_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5496-3

  • Online ISBN: 978-1-4615-1321-6

  • eBook Packages: Springer Book Archive

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