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Altered Expression and Function of Kv Channels in Primary Pulmonary Hypertension

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Potassium Channels in Cardiovascular Biology

Abstract

Primary pulmonary hypertension (PPH) is a progressive, fatal disease that is characterized by a sustained elevation of pulmonary arterial pressure and pulmonary vascular resistance from an unknown cause. The incidence of PPH is about 1–2 per million in the general population, and the mean life expectancy after diagnosis is 2.5 years. Although PPH can occur in individuals of all ages and both genders, it predominantly affects women (Rubin, 1997).

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Author information

Authors and Affiliations

  1. Division of Pulmonary and Critical Care Medicine; Department of Medicine, University of California—San Diego, San Diego, California, 92103-8382, USA

    Jason Xiao-Jian Yuan & Lewis J. Rubin

Authors
  1. Jason Xiao-Jian Yuan
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  2. Lewis J. Rubin
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Editor information

Editors and Affiliations

  1. Walter McKenzie Health Science Centre, University of Alberta Hospital, Edmonton, Alberta, Canada

    Stephen L. Archer

  2. Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Nancy J. Rusch

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Yuan, J.XJ., Rubin, L.J. (2001). Altered Expression and Function of Kv Channels in Primary Pulmonary Hypertension. In: Archer, S.L., Rusch, N.J. (eds) Potassium Channels in Cardiovascular Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1303-2_40

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  • DOI: https://doi.org/10.1007/978-1-4615-1303-2_40

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5487-1

  • Online ISBN: 978-1-4615-1303-2

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