Hemolytic Capacity, Properties, and Activation Requirements of Cobra Venom Factor-Treated Chicken Serum

  • T. L. Koppenheffer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 484)


In contrast to the depletion of complement (C’) activity which occurs following the addition of cobra venom factor (CoVF) to mammalian serum, we have found that CoVF-treated chicken serum retains its lytic potential. We report herein some of the lytic and physiochemical properties of CoVF-treated chicken serum, and compare its activity to that of similarly treated turtle and bullfrog sera.


Hemolytic Activity Lytic Activity Chicken Serum Rana Catesbeiana Cobra Venom 
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  2. Ohta H, Yoshikawa Y, Kai C, Yamanouchi K, Taniguchi H, Komine K-I., Ishijima Y, Okada H. Effect of complement depletion by cobra venom factor in fowlpox virus infection in chickens and chicken embryos. J. Virology, 1986; 57:670–673.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • T. L. Koppenheffer
    • 1
  1. 1.Trinity University, BiologySan Antonio

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