Advertisement

Suppression of the Drosophila Cellular Immune Response by Ganaspis xanthopoda

  • Hsiling Chili
  • Richard Paul Sorrentino
  • Shubha Govind
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 484)

Abstract

The cellular immune response of larvae of Drosophila melanogaster is mediated by two types of hemocyte. Plasmatocytes are small, round, and phagocytic hemocytes that engulf small particles, such as bacteria. When large objects, such as eggs of parasitoid wasps, are introduced into the larval hemocoel, plasmatocytes differentiate into larger, flat, and adhesive lamellocytes. Lamellocytes adhere to one another and wrap around the foreign body, forming capsules. These capsules are often melanized by the second type of hemocyte, called crystal cells, which house enzymes for melanization reactions (Rizki and Rizki, 1984). The capsules render the parasite inert and allow the host to survive. In the larva, plasmatocytes and crystal cells originate in the lymph gland, which is the hematopoietic organ in Drosophila. (Shrestha and Gateff, 1982).

Keywords

Cellular Immune Response Anterior Lobe Posterior Lobe Parasitoid Wasp Hemolymph Sample 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Binari R and Perrimon N (1994).Genes Dey. 8, 300–312.CrossRefGoogle Scholar
  2. Carton Y, Bouletreau M, vanLenteren JC, vanAlphen JCM (1986).In: The Genetics and Biology of Drosophila (Ed. Ashburner M, Carson HL, Thompson JN), New York: Academic Press, 347–394.Google Scholar
  3. Carton Y and Nappi AJ (1997).Parasitol. Today 13(6), 218–227.PubMedCrossRefGoogle Scholar
  4. Hanratty WP and Dearolf CR (1993).Mol. Gen. Genet. 238, 33–37.PubMedGoogle Scholar
  5. Hanratty WP and Ryerse JS (1981).Dey. Biol. 83, 238–249.CrossRefGoogle Scholar
  6. Luo H, Hanratty WP, and Dearolf CR (1995).EMBO J. 14(7), 1412–1420.PubMedGoogle Scholar
  7. Melk JP and Govind S (1999).J. Exp. Biol., 202, 1885–1896.PubMedGoogle Scholar
  8. Nappi AJ, Kmiecik J, and Silvers M (1984).J. Inver. Pathol. 44, 220–227.CrossRefGoogle Scholar
  9. Nappi AJ and Streams FA (1969).J. InsectPhysiol. 15, 1551–1566.Google Scholar
  10. Rizki RM and Rizki TM (1990).Proc. Natl. Acad. Sci. USA 87, 8388–8392.PubMedCrossRefGoogle Scholar
  11. Rizki RM and Rizki TM (1991).J. Exp. Zoology 257, 236–244.CrossRefGoogle Scholar
  12. Rizki TM and Rizki RM (1984).In: Insect ultrastructure (Ed. King RC), New York: Plenum Publishing Co., 2, 574–604.Google Scholar
  13. Rizki TM and Rizki RM (1992).Develop. Comp. Immunol. 16, 103–110.CrossRefGoogle Scholar
  14. Rizki TM and Rizki RM (1994).Ann. New York Acad. Sci. 712, 178–194.CrossRefGoogle Scholar
  15. Schilthuizen M, Nordlander G, Stouthamer R, and vanAlphen JJM (1998).Systematic Entomology 23, 253–264CrossRefGoogle Scholar
  16. Shrestha R and Gateff E (1982). Develop., Growth,and Differ. 24(1), 65–82.CrossRefGoogle Scholar
  17. Strand MR and Pech LL (1995).Annu. Rev. Entomol. 40, 31–56.PubMedCrossRefGoogle Scholar
  18. Vinson SB (1993).In: Insect Immunity (Ed. Pathak JPN), Norwell: KluwerAcademic Publishers, 103–112.Google Scholar
  19. Whitfield JB (1990).Parasitol. Today 6, 381–384.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Hsiling Chili
    • 1
  • Richard Paul Sorrentino
    • 1
    • 2
  • Shubha Govind
    • 1
    • 2
  1. 1.The City CollegeCity UniversityNew York
  2. 2.Graduate School and University CenterCity UniversityNew York

Personalised recommendations