Investigation of 2H(d,n) 3He and 3H(d,n) 4He Fusion Reactions as Alternative Neutron Sources for BNCT

  • J. M. Verbeke
  • J. Vujic
  • K. N. Leung


Beam-shaping assemblies have been designed to moderate high energy neutrons from the fusion reactions 2H(d,n)3He (DD) and 3H(d,n)4He (DT) for use in Boron Neutron Capture Therapy. The low yield of DD is an obstacle for the treatment of Glioblastoma Multiforme. Our analysis shows that the high-energy neutrons from DT can be moderated to epithermal energy range without reducing the neutron flux to a negligible level. With the optimal beam-shaping assembly design for DT, a 1A deuteron beam with energy of l20keV leads to a treatment time of 50 minutes. The dose near the center of the brain obtained with this configuration is about 50% higher than the dose from a typical spectrum produced by the Brookhaven Medical Research Reactor (BMRR), and is comparable to the dose obtained by other accelerator-produced neutron beams.


Dose Distribution Glioblastoma Multiforme Fusion Reaction Neutron Source Neutron Beam 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • J. M. Verbeke
    • 1
    • 2
  • J. Vujic
    • 1
  • K. N. Leung
    • 2
  1. 1.Nuclear Engineering DepartmentUniversity of CaliforniaBerkeleyUSA
  2. 2.Lawrence Berkeley National LaboratoryBerkeleyUSA

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