SLT-Particles for Two-Step Targeting in Boron Neutron Capture Therapy

  • E. Bohl
  • J. Carlsson
  • K. Edwards
  • S. Sjöberg
  • L. Gedda


There are investigations proposing that liposomes, both stabilized and unstabilized, gather at sites of pathology, such as tumors, infections, and inflammations.1, 2, 3, 4 The site-specific uptake of liposomal substances ought to increase with a targeting agent on the liposome. One way to conduct the targeting is to use PEG (polyethylene glycol) as a spacer and conjugate the targeting agent to the terminus of the polymer.5 This conjugated liposome can be named a SLT-particle (stabilized liposome with targeting ligand).


Boron Concentration Boron Content Boron Neutron Capture Therapy Target Step Boron Level 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • E. Bohl
    • 1
  • J. Carlsson
    • 1
  • K. Edwards
    • 2
  • S. Sjöberg
    • 3
  • L. Gedda
    • 1
  1. 1.Biomedical Radiation SciencesRudbeck LaboratoryUppsalaSweden
  2. 2.Physical ChemistryUppsala UniversityUppsalaSweden
  3. 3.Organic ChemistryUppsala UniversityUppsalaSweden

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