Nutrition and Cancer Prevention: New Insights into the Role of Phytochemicals. Future Directions

  • Richard S. Rivlin
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 492)

Abstract

A plant-based diet is important for maintaining health. Substances in fruits and vegetables, alone and in combination with one another, have been shown to have specific anticancer actions. The Ninth Annual Research Conference of the American Institute for Cancer Research has brought together leading scientists who are examining the mechanisms by means of which certain dietary agents may prevent cancer and limit its invasiveness once it has developed.

Keywords

Cholesterol Zinc Obesity Selenium Folate 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Ip C, Lisk DJ. Modulation of phase I and phase II xenobiotic-metabolizing enzymes by selenium-enriched garlic in rats. Nutr Cancer 1997; 28:184–188PubMedCrossRefGoogle Scholar
  2. 2.
    Milner JA. Garlic: its anticarcinogenic and antitumorigenic properties. Nutr Rev. 1996; 54:S82–86PubMedCrossRefGoogle Scholar
  3. 3.
    Bunk MJ, Dnistrian AM, Schwartz MK, Rivlin RS. Regulation of plasma concentrations of vitamin E by dietary zinc. Proc Soc Exp Biol Med. 1988;190:379–384Google Scholar
  4. 4.
    Richter F, Newmark HL, Richter A, et al. Inhibition of Western diet-induced hyperproliferation and hyperplasia in mouse colon by two sources of calcium. Carcinogenesis 1995;16:2685–2689PubMedCrossRefGoogle Scholar
  5. 5.
    Catalona WJ, Richie JP, Ahmann FR, et al. Comparison of digital rectal examination and serum prostate-specific antigen in the early detection of prostate cancer: Results of a multicenter clinical trial of 6,630 men. J Urol. 1994;151:1283–1290PubMedGoogle Scholar
  6. 6.
    Pinto JT, Heston WDW. Prostate specific membrane antigen: A unique folate hydrolase. A review of recent findings. Prostate 1999;1:15–26Google Scholar
  7. 7.
    Jang M, Cai L, Udeani GO, et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997; 275:218–220PubMedCrossRefGoogle Scholar
  8. 8.
    Subbaramaiah K, Chung WJ, Michaluart P, et al. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem. 1998;273:21875–21882PubMedCrossRefGoogle Scholar
  9. 9.
    Rivlin RS. Historical perspective on the use of garlic. J Nutr, 1999 In pressGoogle Scholar
  10. 10.
    Pinto JT, Rivlin RS. Garlic and other allicin vegetables in cancer prevention. In Nutritional Oncology Heber D, Blackburn GL, Go VLM, eds. San Diego: Academic Press, 1999 pp. 393–403Google Scholar
  11. 11.
    Omenn, Goodman GE, Thornquist MD, et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996;334:1150–1155PubMedCrossRefGoogle Scholar
  12. 12.
    Redlich CA, Chung JS, Cullen MR, et al. Effect of long-term beta-carotene and vitamin A on serum cholesterol and triglyceride levels among participants in the carotene and retinol efficacy trial. Atherosclerosis 1999;145:425–432PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Richard S. Rivlin
    • 1
    • 2
    • 3
  1. 1.Clinical Nutrition Research Unit GI-Nutrition Service Memorial Sloan-Kettering Cancer CenterUSA
  2. 2.Nutrition Division-Dept. of Med - Cornell Campus New York-Presbyterian HospitalUSA
  3. 3.Weill Medical College of Cornell UniversityUSA

Personalised recommendations