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Total Exposure

  • Chapter
Residential Exposure Assessment

Abstract

Each of the three previous chapters treated a different exposure pathway (ingestion, inhalation, dermal absorption). This is a reasonable simplification of reality for many, perhaps a majority, of pollutants, since often only one pathway, based on the physical/chemical/biological properties of the agent, dominates exposure. For example, for most volatile organic compounds (VOCs), the compound tends to volatilize from a given medium (e.g., soil or water) into the air and the major exposure is through inhalation of vapors. There are exceptions, however, where multimedia (e.g., lead may be found in ambient air, soil, household dust, drinking water, canned foods) and multipathway (e.g., ingestion of drinking water, inhalation of vapors and dermal contact with water may all be important for a VOC like chloroform) exposures are relevant and a consideration of “total” exposure is necessary in providing a realistic evaluation of residential exposure.

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References

  • Adams, W.C. 1993. Measurement of breathing rate and volume in routinely performed daily activities. Final report. Contract A033-205. California Air Resources Board. Sacramento, California.

    Google Scholar 

  • AIHA (American Industrial Health Association). 1994. AIHA White Paper on Total Human Exposure. Statement adopted by Board of Directors, December 21, 1994. http://www.aiha.org/papers/totalexp.html.

    Google Scholar 

  • Akland, G., T.D. Hartwell, T.R. Johnson, and R. Whitmore. 1985. Measuring human exposure to carbon monoxide in Washington, DC and Denver, CO during the winter of 1982-83. Environ. Sci. Technol.19:911–918.

    Article  CAS  Google Scholar 

  • Amy, G.L., P.A. Chadik, and Z.K. Chowdhury. 1987. Developing models for predicting trihalomethane formation potential and Kinetics. JAWMA 79:89.

    CAS  Google Scholar 

  • Andelman, J.B. 1985a. Human exposures to volatile halogenated organic chemicals in indoor and outdoor air.Environ. Health Perspect. 62:313–318.

    Article  CAS  Google Scholar 

  • Andelman, J.B. 1985b. Inhalation exposure in the home to volatile organic contaminants of drinking water.Sci. Total Environ. 47:443–460.

    Article  CAS  Google Scholar 

  • Andelman, J.B. 1990. Total exposure to volatile organic compounds in potable water. Chapter 20 in: Ram N.M.,R.F. Christman, and K.P. Cantor (eds.). Significance and treatment of volatile organic compounds in water supplies. Lewis Publishers. Chelsea, Michigan.

    Google Scholar 

  • Andelman, J.B., S.M. Meyers, and L.C. Wilder. 1986. Volatilization of organic chemicals from indoor uses of water. Pages 434–440 in: Lester, J.N., R. Perry, and R.M. Sterritt (eds.). Chemicals in the environment.Selper Ltd. London, United Kingdom.

    Google Scholar 

  • Andelman, J.B., L.C. Wilder, and S.M. Myers. 1987. Indoor air pollution from volatile chemicals in water.Pages 37–42 in: Seifert, B., H. Esdorn, M. Fischer, H. Rüden, and J. Wegner (eds.). Indoor Air ’87.Proceedings of the 4th International Conference on Indoor Air Quality and Climate. August 17-21.Volume 1. Institute for Soil, Water, and Air Hygiene. Berlin (West).

    Google Scholar 

  • Aschengrau, A., A. Beiser, D. Bellinger, D. Copenhafer, and M. Weitzman. 1994. The impact of soil lead abatement on urban children’s blood lead levels: Phase II results from the Boston lead-in-soil demonstration project. Environ. Res. 67:125–148.

    Article  CAS  Google Scholar 

  • Ashley, D.L., M.A. Bonin, L. Carkinali, J.M. McCraw, and J.V Wooten. 1994. Blood concentrations of volatile organic compounds in a nonoccupationally exposed U.S. population and in groups with suspected exposure. Clin. Chem. 40:1401–1404.

    CAS  Google Scholar 

  • ATSDR (Agency for Toxic Substances and Disease Registry). 1989. Toxicological Profile for DDT, DDE and DDD. December. U.S. Public Health Service. Atlanta, Georgia.

    Google Scholar 

  • ATSDR (Agency for Toxic Substances and Disease Registry). 1990. Toxicological Profile for Lead.(ATSDR/TP-88/17). U.S. Public Health Service. Atlanta, Georgia.

    Google Scholar 

  • Barkley J., J. Bunch, J.T. Bursey, N. Castillo, S.D. Cooper, J.M. Davis, M.D. Erickson, B.S.H. Harris III, M.Kirkpatrick, L. Michael, S.P. Parks, E. Pellizzari, M. Ray, D. Smith, K. Tomer, R. Wagner, and R.A.Zweidinger. 1980. Gas chromatography mass spectrometry computer analysis of volatile halogenated hydrocarbons in man and his environment-a multimedia environmental study. Biomed. Mass Spectrometry 7:(4)139–147.

    Article  CAS  Google Scholar 

  • Barry, P.S. 1981. Concentrations of lead in the tissues of children. Brit. J. Indus. Med. 38:61–71.

    CAS  Google Scholar 

  • Brown, V.M. and D.R. Crump. 1996. Volatile organic compounds. In: Berry, R.W., V.M. Brown, S.K.D.Coward, D.R. Crump, M. Gavin, C.P. Grimes, D.F. Higham, A.V. Hull, C.A. Hunter, I.G. Jeffery, R.G.Lea, J.W. Llewellyn, and G.J. Raw (eds.). Indoor air quality in homes: Part I. The building research establishment indoor environment study. Construction Research Communications. London, United Kingdom.

    Google Scholar 

  • Cantor, K.P., R. Hoover, P. Hartge, T.J. Mason, D.T. Silverman, R. Altman, D.F. Austin, M.A. Child, C.R.Key, L.D. Marrett, M.H. Myers, A.S. Narayana, L.I. Levin, J.W. Sullivan, G.M. Swanson, D.B. Thomas,and D.W. West. 1987. Bladder cancer, drinking water sources, and tap water consumption: a case-control study. JNCI 79:1269–1279.

    CAS  Google Scholar 

  • CDC (Centers for Disease Control). 1990. Protocol for measurement of volatile organic compounds in human blood using purge/trap gas chromatography mass spectrometry. U.S. Public Health Service. Atlanta,Georgia.

    Google Scholar 

  • Coburn, R.F., R.E. Forster, and P.B. Kane. 1965. Considerations of the physiological variables that determine the blood carboxyhemoglobin concentration in man. J. Clin. Invest. 43:1098–1103.

    Article  Google Scholar 

  • Conner, J.M., G.B. Oldaker III, and J.J. Murphy. 1990. Method for assessing the contribution of environmental tobacco smoke to respirable particles in indoor microenvironments. Environ. Technol.11:189–196.

    Article  Google Scholar 

  • Coulston, F. 1985. Reconsideration of the dilemma of DDT for the establishment of an acceptable daily intake.Reg. Toxicol. Pharmacol. 5:332–383.

    Article  CAS  Google Scholar 

  • Creighton, P.J., P.J. Lioy, and A. Greenburg. 1993. Effects of cooking methodology on benzo(a)pyrene exposure from “home-cooked” bacon and hamburgers and “fast-food chain” hamburgers. J. Exposure Anal.Environ. Epidemiol. 2(Supplement 2):27–44.

    Google Scholar 

  • Dewailly, E., A. Nantel, J-P. Weber, and F. Meyer. 1989. High levels of PCBs in breast milk in Inuit women from arctic Quebec. Bull. Environ. Contam. Toxicol. 43:641–646.

    Article  CAS  Google Scholar 

  • Dowty B., D. Carlisle, J.L. Laseter, and J. Storer. 1975. Halogenated hydrocarbons in New Orleans drinking water and blood plasma. Science 187:75–77.

    Article  CAS  Google Scholar 

  • Duan, N. 1982. Models for human exposure to air pollution. Environ. Internat. 8:305–309.

    Article  CAS  Google Scholar 

  • Duan N. 1985. Application of the microenvironment monitoring approach to assess human exposure to carbonmonoxide. Rand Corporation. Report R-322-EPA. Santa Monica, California.

    Google Scholar 

  • Duan N. 1988. Estimation of microenvironment concentration distributions using integrated exposure measurements. Presented at the Research Planning Conference on Human Activity Patterns. May 10-12,1988. Las Vegas, Nevada.

    Google Scholar 

  • Duan N. 1991. Stochastic microenvironment models for air pollution exposure. J. Exposure Anal. Environ.Epidemiol. 2:235–257.

    Google Scholar 

  • Entz, R., K. Thomas, and G. Diachenko. 1982. Residues of volatile halocarbons in food using headspace gas chromatography. J. Agric. Food Chem. 30:846–849.

    Article  CAS  Google Scholar 

  • Erickson, M.D., B.S.H. Harris III, E.D. Pellizzari, K.B. Tomer, R.D. Waddell and D.A. Whitaker. 1980.Acquisition and chemical analysis of mothers’ milk for selected toxic substances. U.S. Environmental Protection Agency. EPA 560/13-80-029. Washington, D.C.

    Google Scholar 

  • Ershow, A.G. and K.P. Cantor. 1989. Total water and tapwater intake in the United States: population-based estimates of quantities and sources. FASEB. Bethesda, Maryland.

    Google Scholar 

  • Fellin, P. and R. Otson. 1993. Seasonal trends of volatile organic compounds (VOCs) in Canadian homes. Pages 339–343 in: Jaakola, J.J.K., R. Ilmarinen, and O. Seppänen (eds.). Indoor Air ‘93: Proceedings of the 6th International Conference on Indoor Air Quality and Climate Volume 1. Helsinki University of Technology. Espoo, Finland.

    Google Scholar 

  • Fiore, B., H. Anderson, L. Hanrahan, L. Olsen, and W.C. Sonzogni. 1989. Sport fish consumption and body burden levels of chlorinated hydrocarbons: a study of Wisconsin anglers. Arch. Environ. Health 44:82–88.

    Article  CAS  Google Scholar 

  • Frank, R., J. Rasper, M.S. Smout, and H.E. Braun. 1988. Organochlorine residues in adipose tissue, blood and milk from Ontario residents, 1976-1985. Can. J. Pub. Health. 79:150–158.

    CAS  Google Scholar 

  • Fergusson, J.E. 1986. Lead: petrol lead in the environment and its contribution to human blood lead levels. Sci.Total Environ. 50:1–54.

    Article  CAS  Google Scholar 

  • Flegal, A.R. and D.R. Smith. 1995. Measurement of environmental lead contamination and human exposure.Rev. Environ. Contam. Toxicol. 143:1–45.

    Article  CAS  Google Scholar 

  • Gartrell, M., J. Craun, D. Podrebarac, and E. Gunderson. 1985. Pesticides, selected elements, and other chemicals in infant and toddler total diet samples, October 1978-September 1979. JAOAC 68:842–861.

    CAS  Google Scholar 

  • Gartrell, M.J., J.C. Craun, D.S. Podrebarac, and E.L. Gunderson. 1986. Pesticides, selected elements, and other chemicals in infant and toddler total diet samples. October 1980-March 1982. JAOAC 69:138–145.

    Google Scholar 

  • Gephart, L.A., J.G Tell, and L.R. Triemer. 1994. Exposure factors manual. J. Soil Contam. 3:47–117.

    CAS  Google Scholar 

  • Goldstein, B.D., R.G. Tardiff, S.R. Baker, G.F. Hoffnagle, D.R. Murray, PA. Catizone, R.A. Kester, and D.G. Caniparoli. 1992. Valdez air health study. Alyeska Pipeline Service Company. Anchorage, Alaska.

    Google Scholar 

  • Gordon, S., L.A. Wallace, E.D. Pellizzari, and H. O’Neill. 1988. Breath measurements in a clean-air chamber to determine ‘wash-out’ times for volatile organic compounds at environmental concentrations. Atmos.Environ. 22:2165–2170.

    Article  CAS  Google Scholar 

  • Gordon, S.M., D.V. Kenny, and T.J. Kelly. 1992. Continuous real-time breath analysis for the measurement of half-lives of expired volatile organic compounds. J. Exposure Anal. Environ. Epidemiol. Supplement 1:41–54.

    Google Scholar 

  • Gordon, S.M., P.J. Callahan, D.V. Kenny, and J.D. Pleil. 1995. Direct trace analysis of volatile organic compounds in air using ion trap mass spectrometers with filtered noise fields. Presented at the International Symposium on Field Screening Methods for Hazardous Wastes and Toxic Chemicals. Las Vegas,Nevada.

    Google Scholar 

  • Gulson, B.L., K.R. Mahaffey, K.J. Mizon, M.J. Korsch, M.A. Cameron, and G. Vimpani. 1995. Contribution of tissue lead to blood lead in adult female subjects, based on stable lead isotope methods. J. Lab. Clin.Methods 125:703–712.

    CAS  Google Scholar 

  • Gunderson, E.L. 1988. FDA total diet study. April 1982-April 1984. Dietary intakes of pesticides, selected elements, and other chemicals. JAOAC 71:1200–1209.

    CAS  Google Scholar 

  • Hartwell, T.D., C.A. Clayton, R.M. Ritchie, R.W. Whitmore, and H.S. Zelon. 1984. Study of carbon monoxide exposure of residents of Washington, DC and Denver, Colorado. Final report. Research Triangle Institute. Research Triangle Park, North Carolina. NTIS/PB84-184516.

    Google Scholar 

  • Hartwell, T.D., C.A. Clayton, R.W. Michie, R.W. Whitmore, H.S. Zelon, S.M. Jones, and D.A. Whitehurst.1986. Study of carbon monoxide exposure of residents of Washington, DC and Denver, CO. EPA-600/S4-84-031. PB84-183516. Environmental Monitoring Systems Laboratory. Office of Research and Development. U.S. Environmental Protection Agency. Research Triangle Park, North Carolina. 400 pages.

    Google Scholar 

  • Humphrey, H. 1983. Population studies of PCBs in Michigan residents. Chapter 21 in: D’ltri, F. and M. Kamrin (eds.). PCBs: Human and Environmental Hazards. Ann Arbor Science. Lansing, Michigan.

    Google Scholar 

  • Immerman, F.W. and J.L. Schaum. 1990. Nonoccupational pesticide exposure study: Final report. EPA/600-3-90-003. Office of Research and Development. U.S. Environmental Protection Agency. Washington, D.C.

    Google Scholar 

  • Jenkins, R.A., A. Palausky, R.W. Counts, C.K. Bayne, A.B. Dindal, and M.R. Guerin. 1996. Exposure to environmental tobacco smoke in sixteen cities in the United States as determined by personal breathing zone air sampling. J. Exposure Anal. Environ. Epidemiol. 6(4):473–502.

    CAS  Google Scholar 

  • Jensen, A.A. and S.A. Slosach. 1991. Chemical contaminants in human milk. CRC Press. Boca Raton, Florida.

    Google Scholar 

  • Jo, W.K., C.P. Weisel, and P.J. Lioy. 1990a. Routes of chloroform exposure and body burden from showering with contaminated tap water. Risk Anal. 10:575–580.

    Article  CAS  Google Scholar 

  • Jo, W.K., C.P. Weisel, and P.J. Lioy. 1990b. Chloroform exposure and the health risk associated with multiple uses of chlorinated tap water. Risk Anal. 10:581–585.

    Article  CAS  Google Scholar 

  • Johnson, T. 1983. A study of personal exposures to carbon monoxide in Denver, Colorado. Final Report. USEPA Contract Number 68-02-3755. Office of Research and Development. U.S. Environmental Protection Agency. Research Triangle Park, North Carolina.

    Google Scholar 

  • Kelly, T.J., D.V. Kenny, C.W. Spicer, and G.M. Sverdrup. 1989. Continuous analysis of human breath using atmospheric pressure ionization MS/MS with a novel inlet design. In: Proceedings of the 1989 EPA/AWMA International Symposium on Measurement of Toxic and Related Air Pollutants. VIP-13. May 1989. Air and Waste Management Assoc. Pittsburgh, Pennsylvania.

    Google Scholar 

  • Kimbrough, R. 1985. Laboratory and human studies on polychlorinated biphenyls (PCBs) and related compounds. Environ. Health Perspect. 59:99–106.

    Article  CAS  Google Scholar 

  • Kimbrough, R.D. 1987. Human health effects of polychlorinated biphenyls (PCBs) and polybrominated biphenyls (PBBs). Ann. Rev. Pharmacol. Toxicol. 27:87–111.

    Article  CAS  Google Scholar 

  • Krause, C., W. Mailahn, R. Nagel, C. Schulz, B. Seifert, and D. Ullrich. 1987. Occurrence of volatile organic compounds in the air of 500 Homes in the Federal Republic of Germany. Pages 102–106 in: Seifert, B., H. Esdorn, M. Fischer, H. Rüden, and J. Wegner (eds.). Indoor Air ‘87. Proceedings of the 4th International Conference on Indoor Air Quality and Climate. August 17-21. Volume 1. Institute for Soil, Water, and Air Hygiene. Berlin (West).

    Google Scholar 

  • Kreiss, K., M. Zack, R. Kimbrough, L.L. Needham, A.L. Smrek, and B.T. Jones. 1981. Association of blood pressure and polychlorinated biphenyl levels. JAMA 245:2505–2509.

    Article  CAS  Google Scholar 

  • Krotoszynski, B.K., G. Gabriel, and H. O’Neill. 1977. Characterization of human expired air: A promising investigation and diagnostic technique. J. Chromatogr. Sci. 15:239–244.

    CAS  Google Scholar 

  • Krotoszynski, B.K., G.M. Bruneau, and H.J. O’Neill. 1979. Measurement of chemical inhalation exposure in urban populations in the presence of endogenous effluents. J. Analyt. Toxicol. 3:225–234.

    CAS  Google Scholar 

  • Landrigan, P., J. Froines, and K. Mahaffey. 1985. Body lead burden: Summary of epidemiological data on its relation to environmental sources and toxic effects. Pages 421–451 in: Mahaffey, K. (ed.). Dietary and environmental lead: Human health effects. Elsevier. New York, New York.

    Google Scholar 

  • Layton, D.W 1993. Metabolically consistent breathing rates for use in dose assessments. Health Phys. 64:23–36.

    Article  CAS  Google Scholar 

  • Lebret, E., H.J. Van de Weil, D. Noij, and J.S.M. Boleij. 1986. Volatile hydrocarbons in Dutch homes. Environ. Internat. 12(l-4):323–332.

    Article  CAS  Google Scholar 

  • Levesque, B., P. Ayotte, A. Leblanc, E. Dewailly, D. Prud’Homme, R. Lavoie, A. Sylvain, and P. Levallois. 1995. Evaluation of dermal and respiratory chloroform exposure in humans. Environ. Health Perspect. 102:1082–1087.

    Google Scholar 

  • Lindstrom, A.B., V.R. Highsmith, T.J. Buckley, W.J. Pate, and L.C. Michael. 1994. Gasoline-contaminated ground water as a source of residential benzene exposure. J. Exposure Anal. Environ. Epidemiol. 4:183–195.

    CAS  Google Scholar 

  • Lindstrom, A.B., J.D. Pleil, and D.C. Berkoff. 1995. Alveolar breath sampling and analysis to assess trihalomethane exposures during competitive swimming training. Environ. Health Perspect. 105:636–642.

    Article  Google Scholar 

  • Mahaffey, K.R. 1985. Factors modifying susceptibilty to lead toxicity. Pages 373–419 in: Mahaffey, K. (ed.). Dietary and environmental lead: Human health effects. Elsevier. New York, New York.

    Google Scholar 

  • McKinney, J.D., L. Moore, A. Prokopetz, and D.B. Walters. 1984. Validated extraction and cleanup procedure for polychlorinated biphenyls and DDE in human body fluids and infant formula. JAOAC 67(1):122–129.

    CAS  Google Scholar 

  • McKone, T.E. 1993. Linking a PBPK model for chloroform with measured breath concentrations in showers: implications for dermal exposure models. J. Exposure Anal. Environ. Epidemiol. 3(3):339–365.

    CAS  Google Scholar 

  • McKone, T.E. and J. Knezovich. 1991. The transfer of trichloroethylene (TCE) from a shower to indoor air: Experimental measurements and their implications. JAWMA 41:832–837.

    Article  CAS  Google Scholar 

  • Michael, L.C., M.D. Erickson, S.P. Parks, and E.D. Pellizzari. 1980. Volatile environmental pollutants in biological matrices with a headspace purge technique. Anal. Chem. 52:1836–1841.

    Article  CAS  Google Scholar 

  • Miller, D., S. Condon, S. Kutzner, D. Phillips, E. Krueger, R. Timperi, V. Burse, J. Cutler, D. Gute. 1991. Human exposure to polychlorinated biphenyls in greater New Bedford, Massachusetts: A prevalence study. Arch. Environ. Contam. Toxicol. 20:410–416.

    Article  CAS  Google Scholar 

  • Nelson, P.R., D.L. Heavner, B.B. Collie, K.C. Maiolo, and M.W. Ogden. 1992. Effect of ventilation and sampling time on environmental tobacco smoke component ratios. Environ. Sci. Technol. 26:1909–1915.

    Article  CAS  Google Scholar 

  • NCI (National Cancer Institute). 1976. Report on carcinogenesis bioassay of chloroform. NTIS PB-264018. Springfield, Virginia.

    Google Scholar 

  • NYSDOH. New York State Department of Health. 1992. Ambient Air Criteria Document: Polychlorinated Biphenyls (PCBs). Bureau of Toxic Substance Assessment. Albany, New York. 110 pages.

    Google Scholar 

  • NYSLIC (New York State Joint Legislative Commission on Toxic Substances and Hazardous Waste. 1992. Hearing report: Lead contamination in New York State. March 1992. 51 pages.

    Google Scholar 

  • New York State Health Planning Commission. 1977. Report of the ad hoc committee on health implications of PCBs in mothers’ milk. Health Advisory Council. January 7. Albany, New York.

    Google Scholar 

  • Ogden, M.W. and K.C. Maiolo. 1989. Collection and determination of solanesol as a tracer of environmental tobacco smoke in indoor air. Environ Sci Technol. 23:1148–1154.

    Article  CAS  Google Scholar 

  • Ott, W.R. 1982. Concepts of human exposure to air pollution. Environ. Internat. 7:179.

    Article  Google Scholar 

  • Ott, W.R. 1985. Total human exposure: an emerging science focuses on humans as receptors of environmental pollution. Environ. Sci. Technol. 19:880.

    Article  CAS  Google Scholar 

  • Ott, W.R. 1990. Total human exposure: Basic concepts, EPA field studies, and future research needs. JAWMA 40(7):966–975.

    Article  CAS  Google Scholar 

  • Pellizzari, E.D., T.D. Hartwell, B.S.H. Harris III, R.D. Waddell, D.A. Whitaker, and M.D. Erickson. 1982. Purgeable organic compounds in mothers’ milk. Bull Environ. Contam. Toxicol. 28:322–328.

    Article  CAS  Google Scholar 

  • Pellizzari, E.D., R.A. Zweidinger, and L.S. Sheldon. 1985. Breath sampling. Pages 399–411 in: Fishbein, L. and I. O’Neill (eds.). Environmental carcinogens: Methods of analysis and exposure measurement. Volume 7. Some volatile halogenated hydrocarbons. IARC Publication Number 68. World Health Organization. Lyon, France.

    Google Scholar 

  • Pellizzari, E.D., K. Perritt, T.D. Hartwell, L.C. Michael, R. Whitmore, R.W. Handy, D. Smith, and H. Zelon. 1987a. Total exposure assessment methodology (TEAM) study: Elizabeth and Bayonne, New Jersey; Devils Lake, North Dakota; and Greensboro, North Carolina. Volume II. Office of Research and Development. U.S. Environmental Protection Agency. Washington, DC.

    Google Scholar 

  • Pellizzari, E.D., K. Perritt, T.D. Hartwell, L.C. Michael, R. Whitmore, R.W. Handy, D. Smith, and H. Zelon. 1987b. Total exposure assessment methodology (TEAM) study: Selected communities in northern and southern California. Volume III. Office of Research and Development. U.S. Environmental Protection Agency. Washington, D.C.

    Google Scholar 

  • Pellizzari, E.D., K.W. Thomas, J.H. Raymer, D.J. Smith, and S.D. Cooper. 1990. Measurements of exhaled breath using a new portable sampling method. Final Report. Contract Number 68-02-4544. U.S. Environmental Protection Agency. Research Triangle Park, North Carolina.

    Google Scholar 

  • Pleil, J.D. and A.B. Lindstrom. 1995a. Collection of a single alveolar exhaled breath for volatile organic compounds analysis. Amer. J. Indust. Med. 27:109–121.

    Article  Google Scholar 

  • Pleil, J.D. and A.B. Lindstrom. 1995b. Measurement of volatile organic compounds in exhaled breath as collected in evacuated electropolished canisters. J. Chrom B: Biomed Applic. 665:271–279.

    Article  CAS  Google Scholar 

  • Prichard, H.M. and T.F. Gesell. 1981. An estimate of population exposures due to radon in public water supplies in the area of Houston, Texas. Health Phys. 41:599–606.

    Article  CAS  Google Scholar 

  • Quinby, G., J. Armstrong, and W. Durham. 1965. DDT in human milk. Nature 207:726–728.

    Article  CAS  Google Scholar 

  • Rabinowitz, M.B., J.D. Kopple, and G.W. Wetherill. 1980. Effect of food intake and fasting on gastrointestinal lead absorption in humans. Am. J. Clin. Nutrit. 33:1784–1788.

    CAS  Google Scholar 

  • Ramsey, J.C. and M.E. Andersen. 1984. A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. Toxicol. Appl. Pharmacol. 73:159–175.

    Article  CAS  Google Scholar 

  • Raymer, J.H., E.D. Pellizzari, S.D. Cooper, N.P. Castillo, and K.W. Thomas. 1990a. Evaluation of a pharmacokinetic model for volatile organic compounds in breath and of the application of the analytical method to polar VOCs. Final Report. EPA Contract Number 68-02-4544. U.S. Environmental Protection Agency. Research Triangle Park, North Carolina.

    Google Scholar 

  • Raymer, J.H., K.W. Thomas, S.D. Cooper, D.A. Whitaker, and E.D. Pellizzari. 1990b. A device for sampling human alveolar breath for the measurement of expired volatile organic compounds. J. Analyt. Tox. 14:337–344.

    CAS  Google Scholar 

  • Raymer, J.H., K.W. Thomas, E.D. Pellizzari, S.D. Cooper, D.J. Smith, P. Kizakevic, and D. Pugh. 1992a. Breath and blood measurements of individuals exposed to volatile organic chemicals: Elimination from the third compartment. Final Report. Contract Number 68-02-4544. Office of Research and Development. U.S. Environmental Protection Agency. Research Triangle Park, North Carolina.

    Google Scholar 

  • Raymer, J.H., K.W. Thomas, E.D. Pellizzari, D.A. Whitaker, S.D. Cooper, T. Limero, and J.T. James. 1992b. A breath sampling device for measuring human exposure to volatile organic compounds in microgravity. Aviation Space Environ. Med. 65:353–360.

    Google Scholar 

  • Roberts, J.W., M.G. Ruby, and G.R. Warren. 1987. Mutagenic activity of House Dust. Pages 355–367 in: Sandhu, S.S., D.M. De Marini, M.J. Mass, M.M. Moore, and J.L. Mumford (eds.). Short-term bioassays in the analysis of complex environmental mixtures. Volume V. Plenum Press. New York, New York.

    Google Scholar 

  • Roberts, J.W, W.T. Budd, J. Chuang, and R.G. Lewis. 1993. Chemical contaminants in house dust: Occurrences and sources. Pages 27–32 in: Jaakola, J.J.K., R. Ilmarinen, and O. Seppänen (eds.). Indoor Air ‘93: Proceedings of the 6th International Conference on Indoor Air Quality and Climate. Volume 2. Helsinki University of Technology. Espoo, Finland.

    Google Scholar 

  • Rogan, W.J. and B.C. Gladen. 1985. Study of human lactation for effects of environmental contaminants: The North Carolina breast milk and formula project and some other ideas. Environ. Health Perspect. 60:215–221.

    Article  CAS  Google Scholar 

  • Rogan, W.J. and B. Gladen. 1991. PCBs, DDE, and child development at 18 and 24 months. AEP 1(5):407–413.

    CAS  Google Scholar 

  • Rogan, W.J., B.C. Gladen, J.D. McKinney, N. Carreras, P. Hardy, J. Thullen, J. Tingelstad, and M. Tully. 1986a. Polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in human milk: Effects of maternal factors and previous lactation. AJPH 76:172–177.

    Article  CAS  Google Scholar 

  • Rogan, W.J., B.C. Gladen, J.D. McKinney, N. Carreras, P. Hardy, J. Thullen, J. Tinglestad, and M. Tully. 1986b. Neonatal effects of transplacental exposure to PCBs and DDE. J. Pediatr. 109:335–341.

    Article  CAS  Google Scholar 

  • Rogan, W.J., P. Blanto, C. Portier, and E. Stallard. 1991. Should the presence of carcinogens in breast milk discourage breast feeding? Reg. Toxicol. Pharmacol. 13:228–240.

    Article  CAS  Google Scholar 

  • Rook, J.J. 1974. Formation of haloforms during chlorination of natural water. J. Water Treat. Exam. 23:234.

    Google Scholar 

  • Rook, J.J. 1977. Chlorination reactions of fulvic acids in natural waters. Environ. Sci. Technol. 11:478–482.

    Article  CAS  Google Scholar 

  • Schecter, A., P. Purst, C. Furst, H.-A. Meemken, W. Groebel, and D. Quoc Vu. 1989. Levels of polychlorinated dibenzodioxins and dibenzofurans in cow’s milk and in soybean derived infant formulas sold in the United States and other countries. Chemosphere. 19:913–918.

    Article  Google Scholar 

  • Schnoor, J.L., Nitzschke, R.D. Lucas, and J.N. Veenstra. 1979. Trihalomethane yields as a function of precursor molecular weight. Environ. Sci. Technol. 13(9): 1134–1141.

    Article  CAS  Google Scholar 

  • Sheldon, L.S., R.W. Handy, T.D. Hartwell, C. Leininger, and H. Zelon. 1985. Human exposure assessment to environmental chemicals-Nursing mothers study. U.S. Environmental Protection Agency and Research Triangle Institute. Research Triangle Park, North Carolina.

    Google Scholar 

  • Sheldon, L.S., R.W. Handy, T.D. Hartwell, R.W. Whitmore, H.S. Zelon, and E.D. Pellizzari. 1988a. Indoor air quality in public buildings: Volume I. EPA 600/6-88/009a. NTIS PB 89-102503/AS. Office of Research and Development. U.S. Environmental Protection Agency. Washington, D.C.

    Google Scholar 

  • Sheldon, L.S., H.S. Zelon, J. Sickles, C. Eaton, and T. Hartwell. 1988b. Indoor air quality in public buildings: Volume II. EPA 600/6-88/009b. NTIS PB 89-102511/AS. Office of Research and Development. U.S. Environmental Protection Agency. Research Triangle Park, North Carolina.

    Google Scholar 

  • Sheldon, L., A. Clayton, B. Jones, J. Keever, and R. Perritt. 1992. Indoor pollutant concentrations and exposures. Final report June 21, 1989-October 1991. NTIS PB-100060. Research Division, California State Air Resources Board. Sacramento, California.

    Google Scholar 

  • Sheldon, L., D. Whitaker, J. Keever, A. Clayton, and R. Perritt. 1993. Phthalates and PAHs in indoor and outdoor air in a southern California community. Pages 109–114 in: Jaakola, J.J.K., R. Ilmarinen, and O. Seppänen (eds.). Indoor Air ‘93: Proceedings of the 6th International Conference on Indoor Air Quality and Climate. Volume 3. Helsinki University of Technology. Espoo, Finland.

    Google Scholar 

  • Sisovic, A., M. Fugas, and K. Sega. 1996. Assessment of human inhalation exposure to polycyclic aromatic hydrocarbons. J. Exposure Anal. Environ. Epidemiol. 6(4):439–447.

    CAS  Google Scholar 

  • Smith, D.R., J.D. Osterloh, and A.R. Flegal 1996. Use of endogenous, stable lead isotopes to determine release of lead from the skeleton. Environ. Health Perspect. 104:60–66.

    Article  CAS  Google Scholar 

  • Smith, K.R. 1987. Biofuels, air pollution and health. Plenum Press. New York, New York.

    Google Scholar 

  • Smith, K.R. 1993. Fuel combustion, air pollution exposure, and health: The situation in developing countries. Ann. Rev. Energy Environ. 18:529–566.

    Article  Google Scholar 

  • Teorell, T. 1937a. Kinetics of distribution of substances administered to the body. I. The extravascular modes of administration. Arch. Internat. Pharmacodynam. 57:205-225.

    CAS  Google Scholar 

  • Teorell, T 1937b. Kinetics of distribution of substances administered to the body. II. The intravascular mode of administration. Arch. Internat. Pharmacodynam. 57:226-240.

    CAS  Google Scholar 

  • Thomas, K.W., E.D. Pellizzari, and S.D. Cooper. 1991. A canister-based method for collection and GC/MS analysis of volatile organic compounds in human breath. J. Analyt. Toxicol. 15:54-59

    CAS  Google Scholar 

  • Thrall, K.D. and D.V. Kenny. 1996. Evaluation of a carbon tetrachloride physiologically based pharmacokinetic model using real-time breath-analysis monitoring of the rat. Inhalation Toxicol. 8:251-261.

    Article  CAS  Google Scholar 

  • Toyoda M., M. Kobayashi, K. Mitsura, A. Saito, Y. Uno, and K. Sakabe. 1987. Estimation of daily intake of chloroform by Japanese housewives. J. Food Safety 8:219-224.

    Article  Google Scholar 

  • Toyoda, M., K. Takgi, A. Tsurumizu, Y. Saito, H. Kikawa, T. Kawamura, and Y. Sakabe. 1990. Estimation of daily intake of four kinds of trihalomethane by Japanese housewives. J. Food Safety 10:191-200.

    Article  CAS  Google Scholar 

  • USDHHS (United States Department of Health and Human Services). 1991. Strategic plan for the elimination of childhood lead posisoning. Developed for the Risk Management Subcommittee. Committee to Coordinate Environmental Health and Related Programs. Public Health Service. Centers for Disease Control. February.

    Google Scholar 

  • USEPA (U.S. Environmental Protection Agency). 1979. National interim primary drinking water regulations; control of THMs in drinking water; final rule. Office of Drinking Water. Fed Reg. November 29. 44(23l):68624-68707.

    Google Scholar 

  • USEPA (U.S. Environmental Protection Agency). 1986. Air quality criteria for lead. Draft final (EPA-600/ 8-83-028aF). Research Triangle Park, North Carolina.

    Google Scholar 

  • Vaccaro, J.R. 1991. Personal communication. Industrial Hygiene Laboratory. Dow Chemical Company.

    Google Scholar 

  • Vaccaro, J.R., R.J. Nolan, J.M. Hugo, J.L. Pillepich, P.G. Murphy, and M.J. Bartels. 1991. Evaluation of dislodgeable residues and absorbed doses of chlorpyrifos to crawling infants following indoor broadcast applications of chlorpyrifos-based emulsifiable concentrate. Laboratory Project Study ID: DECO-HEH2. 1-1-182(95). The Dow Chemical Company. Midland, Michigan.

    Google Scholar 

  • Vaccaro, J.R., R.J. Nolan, P.G. Murphy, and D.B. Berbrich. 1996. The use of a unique study design to estimate exposure to adults and children to surface and airborne chemicals. American Soceity for Testing Materials. ASTM STP 1287:166-183.

    Google Scholar 

  • Waldman, J.M., P.J. Lioy, A. Greenberg, and J.P. Butler. 1991. Analysis of human exposure to benzo(a)pyrene via inhalation and food ingestion in the total human environmental exposure study (THEES). J. Exposure Anal. Environ. Epidemiol. l(2):193-225.

    Google Scholar 

  • Wallace, L.A. 1983. Carbon monoxide in air and breath of employees in an underground office. JAPCA 33:678-682.

    CAS  Google Scholar 

  • Wallace, L.A. 1987. The TEAM Study: Summary and Analysis: Volume I. 1987. U.S. Environmental Protection Agency. EPA 600/6-87/002a. NTIS PB 88-100060. Washington, D.C.

    Google Scholar 

  • Wallace, L.A. 1991. Comparison of risks from outdoor and indoor exposure to toxic chemicals. Environ. Health Perspect. 95:7-13.

    Article  CAS  Google Scholar 

  • Wallace, L.A. 1997. Human exposure and body burden for chloroform and other trihalomethanes. Critical Reviews in Environ. Sci. Technol. 27:113-194.

    Article  CAS  Google Scholar 

  • Wallace, L.A., R. Zweidinger, M. Erickson, S. Cooper, D. Whitaker, and E.D. Pellizzari. 1982. Monitoring individual exposure: Measurement of volatile organic compounds in breathing-zone air, drinking water, and exhaled breath. Environ. Internat. 8:269-282.

    Article  CAS  Google Scholar 

  • Wallace, L.A., E.D. Pellizzari, T.D. Hartwell, M. Rosenzweig, M. Erickson, C. Sparacino, and H. Zelon. 1984. Personal exposure to volatile organic compounds: I. Direct measurement in breathing-zone air, drinking water, food, and exhaled breath. Environ Res. 35:293-319.

    Article  CAS  Google Scholar 

  • Wallace, L.A., E.D. Pellizzari, T.D. Hartwell, R.W. Whitmore, C. Sparacino, and H. Zelon. 1986a. Total Exposure Assessment Methodology (TEAM) study: Personal exposures, indoor-outdoor relationships, and breath levels of volatile organic compounds in New Jersey. Environ. Internat. 12:369-387.

    Article  CAS  Google Scholar 

  • Wallace, L.A., E.D. Pellizzari, T.D. Hartwell, H. Zelon, C. Sparacino, R. Perritt, and R.W. Whitmore. 1986b. Concentrations of 20 volatile organic compounds in the air and drinking water of 350 residents of New Jersey compared with concentrations in their exhaled breath. J. Occup. Med. 28:603-608.

    Article  CAS  Google Scholar 

  • Wallace, L.A., E.D. Pellizzari, B. Leaderer, T.D. Hartwell, C. Sparacino, R.W Whitmore, L. Sheldon, H. Zelon, and R. Perritt. 1987a. The TEAM study: personal exposure to toxic substances in air, drinking water, and breath of 400 residents of New Jersey, North Carolina, and North Dakota. Environ, Res. 43:290-307.

    Article  CAS  Google Scholar 

  • Wallace, L.A., E.D. Pellizzari, B. Leaderer, T.D. Hartwell, R. Perritt, H. Zelon, and L. Sheldon. 1987b. Emissions of volatile organic compounds from building materials and consumer products. Atmos, Environ. 21:385-393.

    Article  CAS  Google Scholar 

  • Wallace, L.A., E.D. Pellizzari, T.D. Hartwell, R. Whitmore, R. Perritt, and L. Sheldon. 1988. The California TEAM study: breath concentrations and personal exposures to 26 volatile compounds in air and drinking water of 188 residents of Los Angeles, Antioch, and Pittsburg, California. Atmos. Environ. 22:2141-2163.

    Article  CAS  Google Scholar 

  • Wallace, L.A., E.D. Pellizzari, T.D. Hartwell, V. Davis, L.C. Michael, and R.W. Whitmore. 1989. The influence of personal activities on exposure to volatile organic compounds. Environ. Res. 50:37-55.

    Article  CAS  Google Scholar 

  • Wallace, L.A., E.D. Pellizzari, and S. Gordon. 1993. A linear model relating breath concentrations to environmental exposures: application to a chamber study of four volunteers exposed to volatile organic chemicals. J. Exposure Anal. Environ. Epidemiol. 3(1):75-102.

    CAS  Google Scholar 

  • Wallace, L.A., T. Buckley, E.D. Pellizzari, and S. Gordon. 1995. Breath measurements as VOC Biomarkers: EPA’s experience in field and chamber studies. Environ. Health Perspect. 104(Supplement 5):861-869.

    Article  Google Scholar 

  • Wallace, L.A., W.C. Nelson, E.D. Pellizzari, and J.H. Raymer. 1997. A four compartment model relating breath concentrations to low-level chemical exposures: Application to a chamber study of five subjects exposed to nine VOCs. J. Exposure Anal. Environ. Epidemiol. In press.

    Google Scholar 

  • Weisel, C.P., W.K. Jo, and P.J. Lioy. 1990. Routes of chloroform exposure from showering with chlorinated water. In: Measurement of Toxic and Related Air Pollutants: Proceedings of the 1990 EPA/Air and Waste Management Association International Symposium. VIP-17. EPA 600/9-90/026. Air and Waste Management Association. Pittsburgh, Pennsylvania.

    Google Scholar 

  • Weisel, C.P and T.A. Shepard. 1994. Chloroform exposure and the body burden associated with swimming in chlorinated pools. Page 47 in: Wang, R.G.M. (ed.). Water contamination and health: Integration of exposure assessment, toxicology, and risk assessment. Marcel Dekker. New York, New York.

    Google Scholar 

  • Whitmore, R.W. 1988. Design of surveys for residential and personal monitoring of hazardous substances. Atmos. Environ. 22(10):2077-2084.

    Article  CAS  Google Scholar 

  • WHO (World Health Organization). 1979. DDT and its derivatives. Environmental health criteria 9. Geneva, Switzerland.

    Google Scholar 

  • Wilkes, C.R., M.J. Small, J.B. Andelman, N.J. Giardino, and J. Marshall. 1990. Air quality model for volatile constituents from indoor uses of water. Pages 783-788 in: Walkinshaw, D. (ed.). Indoor Air ‘90: proceedings of the 5th international conference on indoor air quality and climate. Volume 2. Toronto, Canada. Canada Mortgage and Housing Association. Ottawa, Canada.

    Google Scholar 

  • Wilkes, C.R., M.J. Small, J.B. Andelman, N.J. Giardino, and J. Marshall. 1992. Inhalation exposure model for volatile chemicals from indoor uses of water. Atmos. Environ. 26A:2227-2236.

    CAS  Google Scholar 

  • Wilson, A.L., S.D. Colome, and Y. Tian. 1993. California residential indoor air quality study. Volume I. Methodology and descriptive statistics. Gas Research Institute, Pacific Gas and Electric Company, San Diego Gas and Electric Company, and Southern California Gas Company. Integrated Environmental Services. Irvine, California.

    Google Scholar 

  • Wilson, N.K., J.C. Chuang, and C. Lyu. 1996. Evaluation of field methods for estimation of exposure of children in low-income families to polycyclic aromatic hydrocarbons. In: Measurement of toxic and related air pollutants: Proceedings of the 1995 EPA/Air and Waste Management Association International Symposium. AWMA. Pittsburgh, Pennsylvania.

    Google Scholar 

  • Zeigler, E.E., B.B. Edwards, R.L. Jensen, K.R. Mahaffey, and S.J. Fomon. 1978. Absorption and retention of lead by infants. Pediat. Res. 12:29-34.

    Article  Google Scholar 

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  1. International Copper Association, New York, New York, USA

    Scott Baker

  2. infoscientific.com, Inc. and risksciences.net, Manassas, Virginia, USA

    Jeffrey Driver

  3. FOCUS GROUP, Tilghman Island, Maryland, USA

    David McCallum

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    Scott Baker

  2. infoscientific.com, Inc. and risksciences.net, Manassas, Virginia, USA

    Jeffrey Driver

  3. FOCUS GROUP, Tilghman Island, Maryland, USA

    David McCallum

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Baker, S., Driver, J., McCallum, D. (2000). Total Exposure. In: Baker, S., Driver, J., McCallum, D. (eds) Residential Exposure Assessment. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1279-0_7

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