Use of Prophylaxis to Prevent Complications of Hemophilia

  • P. M. Mannucci
  • L. Mendolicchio
  • A. Gringeri
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 489)


The main principle of treatment of hemophilia is the replacement of the deficient coagulation factor with plasma-derived or recombinant products. The goal of replacement therapy may be either the prompt arrest of bleeding (episodic or on demand treatment) or its prevention through the regular administration of factor (prophylaxis).


Factor VIII Prophylactic Treatment Joint Damage Bleeding Episode Central Venous Line 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • P. M. Mannucci
    • 1
  • L. Mendolicchio
    • 1
  • A. Gringeri
    • 1
  1. 1.Angelo Bianchi Bonomi Hemophilia and Thrombosis CenterIRCCS Maggiore Hospital and University of MilanItaly

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