Can the Physician Predict the Neuropathologist?

  • Martin N. Rossor
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 487)


The clinical syndrome of dementia encompasses an enormous variety of underlying diseases. Some present as relatively consistent clinicopathological entities, whereas with others the relationship between the clinical syndrome and the underlying molecular pathology can be extremely variable. In general, the most robust associations are between the clinical syndrome and the area of cerebral cortex or subcortical structures involved. The latter may relate to the underlying molecular pathology by virtue of selective vulnerability of particular neuronal systems to a pathological process but not necessarily so.


Clinical Syndrome Semantic Memory Frontotemporal Dementia Molecular Pathology Semantic Dementia 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Martin N. Rossor
    • 1
  1. 1.The National Hospital for Neurology and NeurosurgeryLondonUK

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