Abstract
Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the production of autoantibodies to a spectrum of nuclear antigens, and the development of inflammatory Processes potentially affecting multiple organ systems with varied clinical manifestations. Although the etiology of SLE is still unclear, it has been established that genetic factors play an important role in determining disease susceptibility.
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Liu, K., Wakeland, E.K. (2001). Delineation of the Pathogenesis of Systemic Lupus Erythematosus by Using Murine Models. In: Gupta, S. (eds) Mechanisms of Lymphocyte Activation and Immune Regulation VIII. Advances in Experimental Medicine and Biology, vol 490. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1243-1_1
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DOI: https://doi.org/10.1007/978-1-4615-1243-1_1
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