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Expression and Regulation of Aquaporin-1 and Endothelial Nitric Oxide Synthase in Relationship with Water Permeability Across the Peritoneum

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Molecular Biology and Physiology of Water and Solute Transport

Abstract

Over the past 25 years, peritoneal dialysis (PD) has become an established treatment for end-stage renal disease (ESRD), accounting for about 15% of the total number of patients on dialysis worldwide (Gokal and Mallick 1999). To perform PD, a catheter is inserted into the peritoneal cavity and a solution (dialysate) is infused through it. The dialysate remains in the peritoneal cavity for some hours (dwell time), and is then drained out before fresh dialysate is reinfused (the drainage-reinfusion procedure is called an exchange). Four exchanges are performed daily in continuous ambulatory peritoneal dialysis (CAPD); a mechanical device can also be used to infuse and drain the dialysate during the night, in combination with one or two day-time exchanges (automated peritoneal dialysis, APD) (Gokal and Mallick 1999).

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© 2000 Springer Science+Business Media New York

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Devuyst, O., Combet, S., Balligand, JL., Goffin, E., Verbavatz, JM. (2000). Expression and Regulation of Aquaporin-1 and Endothelial Nitric Oxide Synthase in Relationship with Water Permeability Across the Peritoneum. In: Hohmann, S., Nielsen, S. (eds) Molecular Biology and Physiology of Water and Solute Transport. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1203-5_10

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  • DOI: https://doi.org/10.1007/978-1-4615-1203-5_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5439-0

  • Online ISBN: 978-1-4615-1203-5

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