Skip to main content

Circadian Modulation of Endocrine Secretion

  • Chapter
Circadian Clocks

Part of the book series: Handbook of Behavioral Neurobiology ((HBNE,volume 12))

Abstract

A high degree of temporal organization exists in the endocrine system and is reflected by distinct 24-hour temporal patterns of secretory activity for each endocrine axis. One hormone may be actively secreted in a complex, pulsatile pattern while another may be in a quiescent period. Much of the temporal variability and organization of endocrine activity results from modulatory effects of circadian rhythmicity, a near-24-hour endogenous oscillation originating in the suprachiasmatic nucleus of the hypothalamus and from the effects of sleep/wake homeostasis controlled by diverse and diffuse neural centers, as depicted in Figure 1.. These rhythmic patterns of hormonal secretion are thought to provide internal temporal organization through the coordination of physiologic processes in the time domain, and to also provide an adaptive synchronization of the organism relative to predictable variations of the external environment.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Allan, J., & Czeisler, C. A. (1994). Persistence of the circadian thyrotropin rhythm under constant conditions and after light-induced shifts of circadian phase. Journal of Clinical Endocrinology and Metabolism, 79, 508–512.

    Article  PubMed  CAS  Google Scholar 

  • Arendt, J., & Deacon, S. (1997). Treatment of circadian rhythm disorders-Melatonin. Chronobiology International, 14, 185–204.

    Article  PubMed  CAS  Google Scholar 

  • Armstrong, S. M. (1989). Melatonin and circadian control in mammals Experientia, 45, 932–938.

    Article  PubMed  CAS  Google Scholar 

  • Armstrong, S. M. (1991). Melatonin: A chronobiotic with anti-aging properties? Medical Hypotheses, 34, 300–309.

    Article  PubMed  CAS  Google Scholar 

  • Aschoff, J. (1979). Circadian rhythms: General features and endocrinological aspects. In D. T. Krieger (Ed.), Endocrine rhythms (pp. 1–61). New York: Raven Press.

    Google Scholar 

  • Bliwise, D. L. (1993). Sleep in normal aging and dementia. Sleep, 16, 40–81.

    PubMed  CAS  Google Scholar 

  • Bliwise, D. L. (1994). Normal aging. In M. H. Kryger, T. Roth, & W. C. Dement (Eds.), Principles and practice of sleep medicine (pp. 26–39). Philadephia: Saunders.

    Google Scholar 

  • Born, J., Muth, S., & Fehm, H. L. (1988). The significance of sleep onset and slow wave sleep for nocturnal release of growth hormone (GH) and cortisol. Psychoneuroendocrinology, 13, 233–243.

    Article  PubMed  CAS  Google Scholar 

  • Brabant, G., Brabant, A., Ranft, U., Ocran, K, Köhrle, J., Hesch, R. D., Sc von zür Mühlen, A. (1987). Circadian and pulsatile thyrotropin secretion in euthyroid man under influence of thyroid hormone and glucocorticoid administration. Journal of Clinical Endocrinology and Metabolism, 65, 83–88.

    Article  PubMed  CAS  Google Scholar 

  • Brabant, G., Prank, K., Ranft, U., Schuermeyer, T., Wagner, T. O. F., Hauser, H., Kummer, B., Feistner, H., Hesch, R. D., & von zür Mühlen, A. (1990). Physiological regulation of circadian and pulsatile thyrotropin secretion in normal man and women. Journal of Clinical Endocrinology and Metabolism, 70, 403–409.

    Article  PubMed  CAS  Google Scholar 

  • Brabant, G., Prank, K, Hoang-Vu, C., Hesch, R. D., & von zür Millhen, A. (1991). Hypothalamic regula-tion of pulsatile thyrotropin secretion. Journal of Clinical Endocrinology and Metabolism, 72, 145–150. Brandenberger, G., Charloux, A., Gronfier, C., & Otzenberger, H. (1998). Ultradian rhythms in hydro-mineral hormones. Hormone Research, 49 (3–4), 131–135.

    Google Scholar 

  • Buxton, O. M. Frank, S. A. L’Hermite-Balériaux, M., Leproult, R., Turek, F. W., & Van Cauter, E. (1997). Roles of intensity and duration of nocturnal exercise in causing phase-shifts of human circadian rhythms. American Journal of Physiology (Endocrinology and Metabolism), 273, E536–E542.

    CAS  Google Scholar 

  • Cagnacci, A., Elliott, J. A., & Yen, S. S. C. (1992). Melatonin: A major regulator of the circadian rhythm of core temperature in humans. Journal of Clinical Endocrinology and Metabolism, 75, 447–452.

    Article  PubMed  CAS  Google Scholar 

  • Cassone, V. M. (1990). Effects of melatonin on vertebrate circadian systems. TINS, 13, 457–464.

    PubMed  CAS  Google Scholar 

  • Cleveland, W. S. (1979). Robust locally weighted regression and smoothing scatterplots. Journal of the American Statistical Association, 74, 829–836.

    Article  Google Scholar 

  • Copinschi, G., & Van Canter, E. (1995). Effects of ageing on modulation of hormonal secretions by sleep and circadian rhythmicity. Hormone Research, 43, 20–24.

    Article  PubMed  CAS  Google Scholar 

  • Czeisler, C. A., Chiasera, A. J., & Duffy, J. F. (1991). Research on sleep, circadian rhythms and aging: Applications to manned spaceflight. Experimental Gerontology, 26, 217–232.

    Article  PubMed  CAS  Google Scholar 

  • Dallman, M. E, Strack, A. L., Akana, S. E, Bradbury, M. J., Hanson, E. S., Scribner, K A., & Smith, M. (1993). Feast and famine: Critical role of glucocorticoids with insulin in daily energy flow. Frontiers in Neuroendocrinology, 14, 303–347.

    Article  PubMed  CAS  Google Scholar 

  • Dawson, D., Encel, N., & Lushington, K (1995). Improving adaptation to simulated night shift: Timed exposure to bright light versus daytime melatonin administration. Sleep, 18, 11–21.

    PubMed  CAS  Google Scholar 

  • Deacon, S., & Arendt, J. (1994a). Posture influences melatonin concentrations in plasma and saliva in humans. Neuroscience Letters, 167, 191–194.

    Article  CAS  Google Scholar 

  • Deacon, S. J. & Arendt, J. (1994b). Phase-shifts in melatonin 6-sulphatoxymelatonin and alertness rhythms after treatment with moderately bright light at night. Clinical Endocrinology, 40, 413–420.

    Article  CAS  Google Scholar 

  • Desir, D., Van Cauter, E., L’Hermite, M., Refetoff, S., Jadot, C., Caufriez, A., Copinschi, G., & Robyn, C. (1982). Effects of `jet lag“ on hormonal patterns. III. Demonstration of an intrinsic circadian rhythmicity in plasma prolactin. Journal of Clinical Endocrinology and Metabolism, 55, 849–857.

    Article  PubMed  CAS  Google Scholar 

  • Dollins, A. B., Zhdanova, I. V., Wurtman, R. J., Lynch, H. J., & Deng, M. H. (1994). Effects of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance. Proceedings of the National Academy of Sciences of the USA, 91, 1824–1828.

    Article  PubMed  CAS  Google Scholar 

  • English, J., Middleton, B. A., Arendt, J., & Wirz-Justice, A. (1993). Rapid direct measurement of melatonin in saliva using an iodinated tracer and solid phase second antibody. Annals of Clinical Biochemistry, 30, 415–416

    PubMed  CAS  Google Scholar 

  • Evans, W. S., Sollenberger, M.J., Booth, R. A. J., Rogol, A. D., Urban, R.J., Carlsen, E. C., Johnson, M. L., & Veldhuis, J. D. (1992). Contemporary aspects of discrete peak-detection algorithms. II. The paradigm of the luteinizing hormone signal in women. Endocrine Reviews, 13, 81–104.

    PubMed  CAS  Google Scholar 

  • Finkelstein, J. W., Roffwarg, H. P., Boyar, R. M., Kream, J., & Hellman, L. (1972). Age-related change in the twenty-four-hour spontaneous secretion of growth hormone. Journal of Clinical Endocrinology and Metabolism, 35, 665–670.

    Article  PubMed  CAS  Google Scholar 

  • Folkard, S., Arendt, J., & Clark, M. (1993). Can melatonin improve shift workers’ tolerance of the night shift? Some preliminary findings. Chronobiology International, 10, 315–320.

    Article  PubMed  CAS  Google Scholar 

  • Follenius, M., Brandenberger, G., Hietter, B., Simeoni, M., & Reinhardt, B. (1982). Diurnal cortisol peaks and their relationship to meals. Journal of Clinical Endocrinology and Metabolism, 55, 757–761.

    Article  PubMed  CAS  Google Scholar 

  • Follenius, M., Brandenberger, G., Badasept, J., Libert, J., & Ehrhart, J. (1992). Nocturnal cortisol release in relation to sleep structure. Sleep 15, 21–27.

    PubMed  CAS  Google Scholar 

  • Frank, S., Roland D. C., Sturis, J., Byrne, M. M.Spire, J. P., Refetoff, S., Polonsky, K S., & Van Cauter, E. (1995). Effects of aging on glucose regulation during wakefulness and sleep. American Journal of Physiology, 269, E1006–E1016.

    PubMed  CAS  Google Scholar 

  • Galbo, H. (1995). Integrated endocrine responses and exercise. In L.J. DeGroot (Ed.), Endocrinology (Vol. 3, pp. 2692–2701). Philadelphia: Saunders.

    Google Scholar 

  • Gary, K A., Winokur, A., Douglas, S. D., Kapoor, S., Zaugg, L., & Dinges, D. E (1996). Total sleep deprivation and the thyroid axis: Effects of sleep and waking activity. Aviation, Space and Environmental Medicine, 67, 513–519.

    CAS  Google Scholar 

  • Goichot, B., Brandenberger, G., Sainio, J., Wittersheim, G., & Follenius, M. (1992). Nocturnal plasma thyrotropin variations are related to slow-wave sleep. Journal of Sleep Research, 1, 186–190.

    Article  PubMed  Google Scholar 

  • Golstein, J., Van Canter, E., Desir, D., Noel, P., Spire, J.-P., Refetoff, S., & Copinschi, G. (1983). Effects of “jet lag” on hormonal patterns. IV. Time shifts increase growth hormone release. Journal of Clinical Endocrinology and Metabolism, 56, 433–440.

    Article  PubMed  CAS  Google Scholar 

  • Greenspan, S. L., Klibanski, A., Schoenfeld, D., & Ridgway, E. C. (1986). Pulsatile secretion of thyrotropin in man. Journal of Clinical Endocrinology and Metabolism, 63, 661–668.

    Article  PubMed  CAS  Google Scholar 

  • Gronfier, C., Luthringer, R., Follenius, M., Schaltenbrand, N., Macher, J. P., Muzet, A., & Brandenberger, G. (1995). Temporal link between plasma thyrotropin levels and electroencephalographic activity in man. Neuroscience Letters, 200, 97–100.

    Article  PubMed  CAS  Google Scholar 

  • Gronfier, C., Luthringer, R., Follenius, M., Schaltenbrand, N., Macher, J. P., Muzet, A., & Brandenberger, G. (1996). A quantitative evaluation of the relationships between growth hormone secretion and delta wave electroencephalographic activity during normal sleep and after enrichment in delta waves. Sleep, 19, 817–824.

    PubMed  CAS  Google Scholar 

  • Halberg, F., Tong, Y. L., & Johnson, E. A. (1967). Circadian system phase: An aspect of temporal morphology; procedures and illustrative examples. In Cellular aspects of biorhythms (pp. 20–48). Berlin: Springer-Verlag.

    Google Scholar 

  • Hirschfeld, U., Moreno-Reyes, R., Akseki, E., L’Hermite- Balériaux, M., Leproult, R., Copinschi, G., & Van Cauter, E. (1996). Progressive elevation of plasma thyrotropin during adaptation to simulated jet lag: Effects of treatment with bright light or zolpidem. Journal of Clinical Endocrinology and Metabolism, 81, 3270–3277.

    Article  PubMed  CAS  Google Scholar 

  • Ho, K. Y., Evans, W. S., Blizzard, R. M., Veldhuis, J. D., Merriam, G. R., Samojlik, E., Furlanetto, R., Rogol, A. D., Kaiser, D. L., & Thorner, M. O. (1987). Effects of sex and age on the 24-hour profile of growth hormone secretion in man: Importance of endogenous estradiol concentrations. Journal of Clinical Endocrinology and Metabolism, 64 51–58.

    Article  PubMed  CAS  Google Scholar 

  • Iranmanesh, A., Lizarralde, G., & Veldhuis, J. D., (1991). Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men. Journal of Clinical Endocrinology and Metabolism, 73,1081–1088.

    Article  PubMed  CAS  Google Scholar 

  • Jaffe, C., Turgeon, D., DeMott Friberg, R., Watkins, P., & Barkan, A. (1995). Nocturnal augmentation of growth hormone (GH) secretion is preserved during repetitive bolus administration of GH-releasing hormone: Potential involvement of endogenous somatostatin-A clinical research center study. Journal of Clinical Endocrinology and Metabolism, 80, 3321–3326.

    Article  PubMed  CAS  Google Scholar 

  • Karacan, I., Rosenbloom, A. L., Londono, J. H., Williams, R. L., & Salis, P. J. (1974). Growth hormone levels during morning and afternoon naps. Behavioral Neuropsychiatry, 6, 67–70.

    PubMed  CAS  Google Scholar 

  • Kerkhofs, M., Linkowski, P., & Mendlewicz, J. (1989). Effects of intravenous catheter on sleep in healthy men and in depressed patients. Sleep, 12, 113–119.

    PubMed  CAS  Google Scholar 

  • Laakso, M. L., Hätönen, T., Stenberg, D., Alila, A., & Smith, S. (1993). One-hour exposure to moderate illuminance (500 lux) shifts the human melatonin rhythm. Journal of Pineal Research, 15, 21–26.

    Article  PubMed  CAS  Google Scholar 

  • Landin-Wilhelmsen, K., Wilhelmsen, L., Lappas, G., Rosen, T., Lindstedt, G., Lundberg, P., & Bengtsson, B. (1994). Serum insulin-like growth factor I in a random population sample of men and women: Relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone and osteocalcin. Clinical Endocrinology, 41, 351–357.

    Article  PubMed  CAS  Google Scholar 

  • Lejeune-Lenain, C., Van Cauter, E., Desir, D., Beyloos, M., & Franckson, J. R. M. (1987). Control of circadian and episodic variations of adrenal androgens secretion in man. Journal of Endocrinological Investigation, 10, 267–276.

    PubMed  CAS  Google Scholar 

  • Leproult, R., Buxton, O. M., & Van Cauter, E. (1997). Nocturnal sleep deprivation results in an elevation of cortisol levels the next evening. Sleep, 20, 865–870.

    PubMed  CAS  Google Scholar 

  • Lewy, A. J., & Sack, R. L. (1989). The dim light melatonin onset as a marker for circadian phase position. Chronobiology International, 6, 93–102.

    Article  PubMed  CAS  Google Scholar 

  • Lewy, A. J., Wehr, T. A., Goodwin, F. K, Newsome, D. A., & Markey, S. P. (1980). Light suppresses melatonin secretion in humans. Science, 210, 1267–1269.

    Article  PubMed  CAS  Google Scholar 

  • Lewy, A. J., Ahmed, S., Jackson, J. M. L., & Sack, R. L. (1992). Melatonin shifts human circadian rhythms according to a phase-response curve. Chronobiology International, 9, 380–392.

    Article  PubMed  CAS  Google Scholar 

  • Lewy, A. J., Sack, R. L., Blood, M. L., Bauer, V. K., Cutler, N. L., & Thomas, K. T. (1995). Melatonin marks circadian phase position and resets the endogenous circadian pacemaker in humans. In Circadian clocks and their adjustment (pp. 303–321). Chichester, UK: Wiley.

    Google Scholar 

  • Luger, A., Deuster, P. A., Kyle, S. B., Galucci, W. T., Montgomery, L. C., Gold, P. W., Loriaux, D. L. & Chrousos, G. P. (1987). Acute hypothalamic-pituitary-adrenal responses to the stress of treadmill exercise. New England Journal of Medicine, 316, 1309–1315.

    Article  PubMed  CAS  Google Scholar 

  • Matthews, D. R. (1988). Time series analysis in endocrinology. Acta Paediatrica Scandinavica, Supplement, 347, 55–62.

    PubMed  CAS  Google Scholar 

  • McLeod, B. J., & Craigon, J. (1985). Time series analysis of plasma LH and FSH concentrations as a method of assessing episodic secretion. Journal of Reproduction and Fertility, 74, 575–587.

    Article  PubMed  CAS  Google Scholar 

  • Merriam, G. R., & Wachter, K. W. (1982). Algorithms for the study of episodic hormone secretion. American Journal of Physiology, 243, E310–E318.

    PubMed  CAS  Google Scholar 

  • Mullington, J., Hermann, D., Holsboer, F., & Pollmacher, T. (1996). Age-dependent suppression of nocturnal growth hormone levels during sleep deprivation. Neuroendocrinology, 64, 233–241.

    Article  PubMed  CAS  Google Scholar 

  • O’Meara, N. M., Sturis, J., Van Cauter, E., & Polonsky, K. S. (1993). Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus. Journal of Clinical Investigation, 92, 262–271.

    Article  PubMed  Google Scholar 

  • Oerter, K. E., Guardabasso, V., & Rodbard, D. (1986). Detection and characterization of peaks and estimation of instantaneous secretory rate for episodic pulsatile hormone secretion. Computers and Biomedical Research, 19, 170–191.

    Article  PubMed  CAS  Google Scholar 

  • Okatani, Y., & Sagara, Y. (1993). Role of melatonin in nocturnal prolactin secretion in women with normoprolactinemia and mild hyperprolactinemia. American Journal of Obstetrics and Gynecology, 168, 854–861.

    PubMed  CAS  Google Scholar 

  • Othmer, E., Mendelson, W. B., Levine, W. R., Malarkey, W. B., & Daughaday, W. H. (1974). Sleep-related growth hormone secretion and morning naps. Steroids and Lipids Research, 5, 380–386.

    PubMed  CAS  Google Scholar 

  • Parker, D. C., Rossman, L. G., Pekary, A. E., & Hershman, J. M. (1987). Effect of 64-hour sleep deprivation on the circadian waveform of thyrotropin (TSH): Further evidence of sleep-related inhibition of TSH release. Journal of Clinical Endocrinology and Metabolism, 64, 157–161.

    Article  PubMed  CAS  Google Scholar 

  • Plat, L., Féry, E, L’Hermite-Balériaux, M., Mockel, J., & Van Cauter, E. (1996). Metabolic effects of short-term physiological elevations of plasma cortisol are more pronounced in the evening than in the morning. Paper presented at the Annual Meeting of the American Diabetes Association, San Francisco, California.

    Google Scholar 

  • Prinz, P. N. (1995). Sleep and sleep disorders in older adults. Journal of Clinical Neurophysiology, 12,139–146.

    Article  PubMed  CAS  Google Scholar 

  • Prinz, P. N., Vitiello, M. V., Raskind, M. A., & Thorpy, M. J. (1990). Geriatrics: Sleep disorders and aging. New England Journal of Medicine, 323, 520–526.

    Article  PubMed  CAS  Google Scholar 

  • Prinz, P., Moe, K, Dulberg, E., Larsen, L., Vitiello, M., Toivola, B., & Merriam, G. (1995). Higher plasma IGF-1 levels are associated with increased delta sleep in healthy older men. Journal of Gerontology, 50A, M222–M226.

    CAS  Google Scholar 

  • Quigley, M. E., Ropert, J. F., & Yen, S. S. C. (1981). Acute prolactin release triggered by feeding. Journal of Clinical Endocrinology and Metabolism, 52, 1043–1045.

    Article  PubMed  CAS  Google Scholar 

  • Radomski, M. W., Buguet, A., Montmayeur, A., Bogui, P., Bourdon, L., Doua, F., Lonsdorfer, A., Tapie, P., & Dumas, M. (1995). Twenty-four-hour plasma cortisol and prolactin in human African trypano-somiasis patients and healthy African controls. American Journal of Tropical Medicine and Hygiene, 52, 281–286.

    PubMed  CAS  Google Scholar 

  • Rosenthal, N. E. (1991). Plasma melatonin as a measure of the human clock. Journal of Clinical Endocrinology and Metabolism, 73, 225–226.

    CAS  Google Scholar 

  • Rossmanith, W. G., Boscher, S., Ulrich, U., & Benz, R. (1993). Chronobiology of prolactin secretion in women: Diurnal and sleep-related variations in the pituitary lactotroph sensitivity. Neuroendocrinology, 58, 263–271.

    Article  PubMed  CAS  Google Scholar 

  • Royston, J. P. (1989). The statistical analysis of pulsatile hormone secretion data. Clinical Endocrinology, 30, 201–210.

    Article  PubMed  CAS  Google Scholar 

  • Sassin, J. F., Parker, D. C., Mace, J. W., Gotlin, R. W., Johnson, L. C., & Rossman, L. G. (1969). Human growth hormone release: Relation to slow-wave sleep and sleep-waking cycles. Science, 165, 513–515.

    Article  PubMed  CAS  Google Scholar 

  • Seifritz, E., Hemmeter, U., Trachsel, L., Lauer, C., Hatzinger, M., Emrich, H., Holsboer, F., & HolsboerTrachsler, E. (1995). Effects of flumazenil on recovery sleep and hormonal secretion after sleep deprivation in male controls. Psychopharmacology (Berlin) 120, 449–456.

    Article  CAS  Google Scholar 

  • Shanahan, T. L., & Czeisler, C. A. (1991). Light exposure induces equivalent phase shifts of the endogenous circadian rhythms of circulating plasma melatonin and core body temperature in men. Journal of Clinical Endocrinology and Metabolism, 73, 227–235.

    Article  PubMed  CAS  Google Scholar 

  • Spath-Schwalbe, E., Gofferje, M., Kern, W., Born, J., & Fehm, H. L. (1991). Sleep disruption alters nocturnal ACTH and cortisol secretory patterns. Biological Psychiatry, 29, 575–584.

    Article  PubMed  CAS  Google Scholar 

  • Spiegel, K, Follenius, M., Simon, C., Saini, J., Ehrhart, J., & Brandenberger, G. (1994). Prolactin secretion and sleep. Sleep, 17, 20–27.

    PubMed  CAS  Google Scholar 

  • Spiegel, K, Weibel, L., Gronfier, C., Brandenberger, G., & Follenius, M. (1996). Twenty-four hour prolactin profiles in night workers. Chronobiology International, 13, 283–293.

    Article  PubMed  CAS  Google Scholar 

  • Studs, J., Polonsky, K. S., Shapiro, E. T., Blackman, J. D., O’Meara, N. M., & Van Canter, E. (1992). Abnormalities in the ultradian oscillations of insulin secretion and glucose levels in type 2 (noninsulin-dependent) diabetic patients. Diabetologia, 35, 681–689.

    Article  Google Scholar 

  • Takahashi, Y., Kipnis, D. M., & Daughaday, W. H. (1968). Growth hormone secretion during sleep. Journal of Clinical Investigation, 47, 2079–2090.

    Article  PubMed  CAS  Google Scholar 

  • Turek, E W., Sc Van Cauter, E. (1993). Rhythms in reproduction. In E. Knobil, J. J. Neill, et al., (Eds.), The physiology of reproduction, (pp. 1789–1830). New York: Raven Press.

    Google Scholar 

  • Tzischinsky, O., & Lavie, P. (1994). Melatonin possesses time-dependent hypnotic effects. Sleep, 17, 638–645.

    PubMed  CAS  Google Scholar 

  • Urban, R. J., Evans, W. S., Rogol, A. D., Kaiser, D. L., Johnson, M. L., & Veldhuis, J. D. (1988). Contemporary aspects of discrete peak-detection algorithms. I. The paradigm of the luteinizing hormone pulse signal in men. Endocrine Reviews, 9, 3–37.

    Article  PubMed  CAS  Google Scholar 

  • Van Cauter, E. (1979). Method for characterization of 24-h temporal variation blood constituents. American Journal of Physiology, 237, E255–E264.

    PubMed  Google Scholar 

  • Van Cauter, E. (1987). Time series analysis in pulse detection techniques. In T. O. F. Wagner & M. Filicori (Eds.), Episodic hormone secretion: From basic science to clinical application (pp. 51–60). Hameln, Germany: TM-Verlag.

    Google Scholar 

  • Van Cauter, E. (1988). Estimating false-positive and false-negative errors in analyses of hormonal pulsatility. American Journal of Physiology, 254, E786–E794.

    PubMed  Google Scholar 

  • Van Cauter, E. (1990). Computer-assisted analysis of endocrine rhythms. In D. Rodbard & G. Forti (Eds.), Computers in endocrinology (pp. 59–70). New York: Raven Press.

    Google Scholar 

  • Van Cauter, E., & Aschoff, J. (1989). Endocrine and other biological rhythms. In L. J. DeGroot (Ed.), Endocrinology (Vol. 3, pp. 2658–2705). Philadelphia: Saunders.

    Google Scholar 

  • Van Canter, E., & Copinschi, G. (1999). Interactions between growth hormone secretion and sleep. In R. G. Smith & M. O. Thorner (Eds.), Human growth hormone: Research and clinical practice (pp. 261–284). Totowa, NJ: Humana Press.

    Google Scholar 

  • Van Cauter, E., & Honinckx, E. (1985). Pulsatility of pituitary hormones. Experimental Brain Research Supplement, 12, 41–60.

    Article  Google Scholar 

  • Van Cauter, E., & Turek, E W. (1995). Endocrine and other biological rhythms. In L. J. DeGroot (Ed.), Endocrinology (pp. 2487–2548). Philadelphia: Saunders.

    Google Scholar 

  • Van Cauter, E., L’Hermite, M., Copinschi, G., Refetoff, S., Desir, D., & Robyn, C. (1981). Quantitative analysis of spontaneous variations of plasma prolactin in normal man. American Journal of Physiology, 241, E355–E363.

    PubMed  Google Scholar 

  • Van Cauter, E., van Coevorden, A., & Blackman, J. D. (1990). Modulation of neuroendocrine release by sleep and circadian rhythmicity. In S. Yen & W. Vale (Eds.), Advances in neuroendocrine regulation of reproduction, (pp. 113–122). Norwell, MA: Serono Symposia, USA.

    Google Scholar 

  • Van Cauter, E., Blackman, J. D., Roland, D., Spire, J. P., Refetoff, S., & Polonsky, K. S. (1991). Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep. Journal of Clinical Investigation, 88, 934–942.

    Article  PubMed  Google Scholar 

  • Van Cauter, E., Kerkhofs, M., Caufriez, A., Van Onderbergen, A., Thorner, M. O., & Copinschi, G. (1992a). A quantitative estimation of GH secretion in normal man: Reproducibility and relation to sleep and time of day. Journal of Clinical Endocrinology and Metabolism, 74, 1441.

    Article  Google Scholar 

  • Van Cauter, E., Shapiro, E. T., Tillil, H., & Polonsky, K S. (1992b). Circadian modulation of glucose and insulin responses to meals: Relationship to cortisol rhythm. American Journal of Physiology, 262, E467–E475.

    Google Scholar 

  • Van Canter, E., Sturis, J., Byrne, M. M., Blackman, J. D., Leproult, R., Ofek, G., L’Hermite-Balériaux, M., Refetoff, S., Turek, E W., & Van Reeth, O. (1994). Demonstration of rapid light-induced advances and delays of the human circadian clock using hormonal phase markers. American Journal ofPhysiology, 266, E953–E963.

    Google Scholar 

  • Van Cauter, E., Leproult, R., & Kupfer, D.J. (1996). Effects of gender and age on the levels and circadian rhythmicity of plasma cortisol. Journal of Clinical Endocrinology and Metabolism, 81, 2468–2473.

    Article  PubMed  Google Scholar 

  • Van Canter, E., Plat, L., Scharf, M., Leproult, R., Cespedes, S., L’Hermite-Balériaux, M., & Copinschi, G. (1997a). Simultaneous stimulation of slow-wave sleep and growth hormone secretion by gammahydroxybutyrate in normal young men. Journal of Clinical Investigation, 100, 745–753.

    Article  Google Scholar 

  • Van Cauter, E., Polonsky, K. S., & Scheen, A.J. (1997b). Roles of circadian rhythmicity and sleep in human glucose regulation. Endocrine Reviews, 18, 716–738.

    Article  Google Scholar 

  • van Coevorden, A., Mockel, J., Laurent, E., Kerkhofs, M., L’Hermite-Balériaux, M., Decoster, C., Nève, P., & Van Cauter, E. (1991). Neuroendocrine rhythms and sleep in aging. American Journal of Physiology, 260, E651– E661.

    PubMed  Google Scholar 

  • Van Reeth, O., Sturis, J., Byrne, M. M., Blackman, J. D., L’Hermite-Balériaux, M., Leproult, R., Oliner, C., Refetoff, S., Turek, F. W., &Van Cauter, E. (1994). Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin in normal men. American Journal of Physiology, 266, E964–E974.

    PubMed  Google Scholar 

  • Veldhuis, J. D., & Johnson, M. L. (1986). Cluster analysis: A simple, versatile, and robust algorithm for endocrine pulse detection. American Journal of Physiology, 250, E486–E493.

    PubMed  CAS  Google Scholar 

  • Veldhuis, J. D., & Johnson, M. L. (1988). Operating characteristics of the hypothalamo–pituitarygonadal axis in men: Circadian, ultradian, and pulsatile release of prolactin and its temporal coupling with luteinizing hormone. Journal of Clinical Endocrinology and Metabolism, 67, 116–123.

    Article  PubMed  CAS  Google Scholar 

  • Veldhuis, J., Iranmanesh, A., Lizarralde, G., & Johnson, M. (1989a). Amplitude modulation of a burstlike mode of cortisol secretion subserves the circadian glucocorticoid rhythm. American Journal of Physiology, 257, E6– E14.

    CAS  Google Scholar 

  • Veldhuis, J. D., Iranmanesh, A., Johnson, M. L., & Lizarralde, G. (1989b). Amplitude, but not frequency, modulation of adrenocorticotropin secretory bursts gives rise to the nyctohemeral rhythm of the corticotropic axis in man. Journal of Clinical Endocrinology and Metabolism, 71, 452–463.

    Article  Google Scholar 

  • Veldhuis, J. D., Iranmanesh, A., Johnson, M. L., & Lizarralde, G. (1990). Twenty-four-hour rhythms in plasma concentrations of adenohypophyseal hormones are generated by distinct amplitude and/or frequency modulation of underlying pituitary secretory bursts. Journal of Clinical Endocrinology and Metabolism, 71, 1616–1623.

    Article  PubMed  CAS  Google Scholar 

  • Veldhuis, J. D., Johnson, M. L., Lizarralde, G., & Iranmanesh, A. (1992). Rhythmic and nonrhythmic modes of anterior pituitary gland secretion. Chronobiology International, 9, 371–379.

    Article  PubMed  CAS  Google Scholar 

  • Vermeulen, A. (1987). Nyctohemeral growth hormone profiles in young and aged men: Correlation with somatomedin-C levels. Journal of Clinical Endocrinology and Metabolism, 64, 884–888.

    Article  PubMed  CAS  Google Scholar 

  • Waldstreicher, J., Duffy, J. F., Brown, E. N., Rogacz, S., Allan, J. S., & Czeisler, C. A. (1996). Gender differences in the temporal organization of prolactin (PRL) secretion: Evidence for a sleep-independent circadian rhythm of circulating PRL levels—A Clinical Research Center study. Journal of Clinical Endocrinology and Metabolism, 81, 1483–1487.

    Article  PubMed  CAS  Google Scholar 

  • Weaver, D. R., Rivkees, S. A., Carlson, L. L., & Reppert, S. M. (1991). Localization of melatonin receptors in mammalian brain. In D. C. Klein, R. Y. Moore, & S. M. Reppert (Eds.), Suprachiasmatic nucleus: The mind’s clock (pp. 289–308). New York: Oxford University Press.

    Google Scholar 

  • Wehr, T., Moul, D., Barbato, G., Giesen, H., Seidel, J., Barker, C., & Bender, C. (1993). Conservation of photoperiod-responsive mechanisms in humans. American Journal of Physiology, 265, R846–R857.

    CAS  Google Scholar 

  • Weibel, L., Brandenberger, G., Goichot, B., Spiegel, K, Ehrhart, J., & Follenius, M. (1995a). The circadian thyrotropin rhythm is delayed in regular night workers. Neuroscience Letters, 187, 83–86.

    Article  CAS  Google Scholar 

  • Weibel, L., Follenius, M., Spiegel, K, Ehrhart, J., & Brandenberger, G. (1995b). Comparative effect of night and daytime sleep on the 24-hour cortisol secretory profile. Sleep, 18, 549–556.

    CAS  Google Scholar 

  • Weibel, L., Follenius, M., Spiegel, K, Gronfier, C., & Brandenberger, G. (1997a). Growth hormone secretion in night workers. Chronobiology International, 14, 49–60.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer Science+Business Media New York

About this chapter

Cite this chapter

Van Cauter, E., Buxton, O.M. (2001). Circadian Modulation of Endocrine Secretion. In: Takahashi, J.S., Turek, F.W., Moore, R.Y. (eds) Circadian Clocks. Handbook of Behavioral Neurobiology, vol 12. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1201-1_26

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-1201-1_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5438-3

  • Online ISBN: 978-1-4615-1201-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics