Abstract
Although the association of estrogen (E) deficiency with postmenopausal bone loss and osteoporosis has been appreciated for over 40 years, the mechanisms by which estrogen preserves bone mass have not been clear. However, over the last decade, there has been an enormous increase in our understanding of the mechanisms by which this occurs. E action on bone can be understood at several different levels of organization. In this paper, we will discuss E action on bone and calcium metabolism at the organ, tissue, cellular, and molecular levels.
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Riggs, B.L. (2002). Mechanisms of Estrogen Regulation of Bone Turnover and Bone Mass. In: Lobo, R.A., Crosignani, P.G., Paoletti, R., Bruschi, F. (eds) Women’s Health and Menopause. Medical Science Symposia Series, vol 17. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1061-1_3
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DOI: https://doi.org/10.1007/978-1-4615-1061-1_3
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