Abstract
Over the last two decades, the incidence of many fungal diseases in the United States has increased dramatically, mostly due to major advances in health care, as well as various demographic changes. These include aging of the population, the HIV epidemic, and the increasingly aggressive medical therapies available. Broad-spectrum antibiotics are more widely used than ever, especially among neutropenic and surgical patients in the intensive care unit (ICU). Potent cytotoxic chemotherapy, as well as more effective immunomodulation therapy, has resulted in prolonged survival of cancer patients and transplant recipients, but also in periods of severe immunosuppression and increased risk for fungal infections. Dramatic changes have also been achieved in neonatal care, leading to improved survival of premature infants.
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Hajjeh, R.A., Lyon, G.M. (2002). Epidemiology of Candida Infections in the Intensive Care Unit. In: Barnes, R.A., Warnock, D.W. (eds) Fungal Infection in the Intensive Care Unit. Perspectives on Critical Care Infectious Diseases, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0977-6_1
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DOI: https://doi.org/10.1007/978-1-4615-0977-6_1
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