Abstract
For many years myopathy has been known to be part of the osteomalacic symptom complex 1–7. Generally, hypovitaminosis D myopathy (HDM) has been considered a symptom occasionally seen in patients suffering from osteomalacic bone disease, rather than an early presenting symptom of vitamin D deficiency. However, already in 1975 in a group of 30 patients with biopsy proven osteomalacia, Skaria et al 5 found that myopathy was the presenting symptom in 30%, but was clinically detectable in 96.7% of patients. Thus, myopathy is a prominent symptom in osteomalacia. Recently it was shown by Glerup et al 8 that HDM precedes bone involvement in osteomalacia caused by vitamin D deficiency.
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Glerup, H., Eriksen, E.F. (2002). Hypovitaminosis D Myopathy. In: Holick, M.F. (eds) Biologic Effects of Light 2001. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0937-0_18
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DOI: https://doi.org/10.1007/978-1-4615-0937-0_18
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