Subicular Place Cells Show Similar Firing Fields Across Different Environments: Comparison with Hippocampal Place Cells
The phenomenon of Place Cell activity is most often examined during sessions in which a rat travels freely through a single, experimenter-devised recording chamber or maze (see Chapters 1,2,3, and 4). The basic phenomenon consists of the fact that each individual cell fires when the rat is in one particular region of that environment, and is silent when the rat is located outside of this range. Since each cell has a different spatial field, this means that each position the rat can occupy is signaled by activity in a different set of Place Cells. In this way, the cells form a “map” of the environment. This is illustrated schematically in Figure 1A.
KeywordsPath Integration Firing Pattern Place Cell Attractor Layer Hippocampal Cell
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- Georgopoulos A.P., Kalaska J.F., Caminiti R., Massey J.T. (1984) The representation of movement direction in the motor cortex: single cell and population studies. In Dynamic Aspects of Neocortical Function, G.M. Edleman, W.E. Gall, W.M. Cowan, Eds. New York: John Wiley and Sons, (pp 501–624).Google Scholar
- Kubie, J.L., Ranck, J.B. Jr. (1982) Tonic and phasic firing of rat hippocampal complex spike cells in three different situations: Context and place. Adv. Behav. Biol., 26: 89–98.Google Scholar
- McNaughton, B.L., Barnes, C.A., Gerrard, J.L., Gothard, K., Jung, M.W., Knierim, J.J., Kudrimoti, H., Quin, Y., Skaggs, W.E., Suster, M., Weaver, K.L. (1996) Deciphering the hippocampal polyglot: The hippocampus as a path integration system. J. Expt. Biol., 199: 173–185.Google Scholar