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Familial Dysautonomia in Review: Diagnosis and Treatment of Ocular Manifestations

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Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 506))

Abstract

Familial dysautonomia (FD) is a rare genetic disease belonging to a group of disorders known as hereditary sensory and autonomic neuropathies. Incomplete sensory and autonomic neuron development results in general sensory dysfunction and variable autonomic dysfunction. Currently, only about 50% of FD patients reach 30 years of age.1 With rare exception, FD, also known as HSAN (or HSN) type III and Riley-Day syndrome, affects patients of Ashkenazi Jewish descent and is included among the Jewish genetic diseases (e.g., Gaucher disease, Tay-Sachs disease).

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Author information

Authors and Affiliations

  1. Allergan, Inc., Irvine, California, USA

    Cathleen A. Josaitis & Martin Matisoff

Authors
  1. Cathleen A. Josaitis
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  2. Martin Matisoff
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Editor information

Editors and Affiliations

  1. Schepens Eye Research Institute, Boston, Massachusetts, USA

    David A. Sullivan , Darlene A. Dartt  & Rose M. Sullivan ,  & 

  2. Harvard Medical School, Boston, Massachusetts, USA

    David A. Sullivan  & Darlene A. Dartt  & 

  3. Allergan, Inc., Irvine, California, USA

    Michael E. Stern

  4. Tokyo Dental College, Chiba, Japan

    Kazuo Tsubota

  5. Ichikawa General Hospital, Chiba, Japan

    Kazuo Tsubota

  6. University of New Orleans, New Orleans, Louisiana, USA

    B. Britt Bromberg

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© 2002 Kluwer Academic/Plenum Publishers

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Josaitis, C.A., Matisoff, M. (2002). Familial Dysautonomia in Review: Diagnosis and Treatment of Ocular Manifestations. In: Sullivan, D.A., Stern, M.E., Tsubota, K., Dartt, D.A., Sullivan, R.M., Bromberg, B.B. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3. Advances in Experimental Medicine and Biology, vol 506. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0717-8_9

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  • DOI: https://doi.org/10.1007/978-1-4615-0717-8_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5208-2

  • Online ISBN: 978-1-4615-0717-8

  • eBook Packages: Springer Book Archive

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