Ocular TFF-Peptides: New Mucus-Associated Secretory Products of Conjunctival Goblet Cells
The ocular surface is overlaid by a three-layered tear film, 35–45 _m thick, that serves as a lubricant and protective barrier,1 and is essential for the normal function of the human eye. The outer lipid layer is secreted by the meibomian glands, and the intermediate aqueous layer is produced by the lacrimal glands. The inner layer of about 30 _m, contains mucins as its major structural components. These large glycoconjugates regulate the rheological properties defined by the tear breakup time of the ocular mucus. This parameter changes in the course of pathologic conditions such as dry eye disease.
KeywordsSubmandibular Gland Lacrimal Gland Secretory Function Congenic Mouse Chronic Autoimmune Disorder
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