Abstract
Aging is accompanied by morphological and secretory changes in lacrimal and salivary glands (LG and SG) that correlate with manifestations of dry eye and mouth among the elderly.1–6 Apart from systemic diseases, hormonal imbalances and the use of medications affect organ functions during aging.7 A concomitant impairment of the mechanisms of signal transduction may contribute to specific organ dysfunction.8–10
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Rocha, E.M., Carvalho, C.R.O., Saad, M.J.A., Velloso, L.A. (2002). The Influence of Aging in the Insulin-Signaling System in Rat Exocrine Glands. In: Sullivan, D.A., Stern, M.E., Tsubota, K., Dartt, D.A., Sullivan, R.M., Bromberg, B.B. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3. Advances in Experimental Medicine and Biology, vol 506. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0717-8_3
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DOI: https://doi.org/10.1007/978-1-4615-0717-8_3
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