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The Influence of Aging in the Insulin-Signaling System in Rat Exocrine Glands

  • Eduardo M. Rocha
  • Carla R. O. Carvalho
  • Mário J. A. Saad
  • Lício A. Velloso
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 506)

Abstract

Aging is accompanied by morphological and secretory changes in lacrimal and salivary glands (LG and SG) that correlate with manifestations of dry eye and mouth among the elderly.1–6 Apart from systemic diseases, hormonal imbalances and the use of medications affect organ functions during aging.7 A concomitant impairment of the mechanisms of signal transduction may contribute to specific organ dysfunction.8–10

Keywords

Respiratory Syncytial Virus Herpes Simplex Virus Type Corneal Epithelial Cell Corneal Stroma Chemokine Expression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic/Plenum Publishers 2002

Authors and Affiliations

  • Eduardo M. Rocha
    • 1
  • Carla R. O. Carvalho
    • 2
  • Mário J. A. Saad
    • 1
  • Lício A. Velloso
    • 1
  1. 1.Laboratory of Clinical Physiopathology, Department of Clinical MedicineFCM-UNICAMPCampinasBrazil
  2. 2.Department of PhysiologyICB-USPSão PauloBrazil

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