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Identification of Androgen-Regulated Genes in the Lacrimal Gland

  • M. Liu
  • S. M. Richards
  • F. Schirra
  • H. Yamagami
  • B. D. Sullivan
  • D. A. Sullivan
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 506)

Abstract

Androgens exert a significant influence on the cellular architecture, protein synthesis, immune function and secretory activity of the lacrimal gland.1 In fact, these hormone effects appear to account for many of the gender-related differences that occur in the anatomy, biochemistry, physiology and immunology of lacrimal tissue in a variety of species.1 We hypothesize that androgen actions are mediated primarily through androgen receptors, which exist in lacrimal gland epithelial cells,2–4 and involve the regulation of specific target genes. The purpose of this investigation was to identify the genes controlled by androgens in lacrimal tissue.

Keywords

Contact Lens Wearer Oral Immunization Acanthamoeba Keratitis Corneal Infection Intramuscular Immunization 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
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Copyright information

© Kluwer Academic/Plenum Publishers 2002

Authors and Affiliations

  • M. Liu
    • 1
  • S. M. Richards
    • 1
  • F. Schirra
    • 1
  • H. Yamagami
    • 1
  • B. D. Sullivan
    • 1
  • D. A. Sullivan
    • 1
  1. 1.Schepens Eye Research Institute and the Department of OphthalmologyHarvard Medical SchoolBostonUSA

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