The Role of Basal Ganglia in Visuo- Motor Coordination, Insights from Different Disease Conditions
Visuo motor coordination (VMC) is a term used in reference to actions directed towards visually presented objects. Relevant actions may be reaching, grasping, tracking or any combination of the above. The common denominator of all such actions is the need to translate visual information into a coordinated sequence of muscle contractions, such that the resulting movement will meet its goal. Naturally, a visually based computational process, a motor planning stage and a motor executional stage must be involved. In recent years a wealth of knowledge has been gained about the anatomy and physiology of these processes but the focus has mostly been on cortical circuits and processes. Consequently, despite documented basal ganglia involvement in VMC, impairments in this functional domain are not considered in association with basal ganglia dysfunction. Ignoring the role of basal ganglia in VMC hinders our understanding of how the brain derives and executes movement plans, in addition to missing an opportunity to better understand the role of the basal ganglia in motor planning and control.
KeywordsDepression Dopamine Schizophrenia Neurol Levodopa
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