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Interspecies Comparisons for the C3-C4 Propriospinal System: Unresolved Issues

  • Peter A. Kirkwood
  • M. A. Maier
  • Roger N. Lemon
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 508)

Abstract

There are conflicting views on the functional importance of the system of C3-C4 propriospinal neurones in the macaque, although the two sets of observations from the opposing laboratories are actually quite similar, both making the system appear much weaker than its well-known equivalent in the cat One group asserts, mainly via evidence derived from experiments with strychnine, that this is a consequence simply of inhibition of the propriospinal neurone. However, we ague here that this judgement is premature and that much more needs to be known about the neurones involved and their connectivity before the analogy with the system in the cat is safe. This is particularly important because of a similar analogy which has been made with respect to measurements in human subjects.

Keywords

Transcranial Magnetic Stimulation Pyramidal Tract Experimental Brain Research Lateral Reticular Nucleus Interspecies Comparison 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Peter A. Kirkwood
    • 1
  • M. A. Maier
    • 2
  • Roger N. Lemon
    • 1
  1. 1.Sobell Department for Motor Neuroscience and Movement DisordersInstitute of Neurology, University College London, Queen SquareLondonUK
  2. 2.INSERM U483Université Pierre et Marie CurieParisFrance

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