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Reflections on Spinal Reflexes

  • Douglas G. Stuart
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 508)

Abstract

Over the past four decades, the understanding of proprioceptive spinal reflexes has advanced far more rapidly than generally considered. This problem could be largely obviated in undergraduate and graduate training programs if the topic of reflexes was introduced subsequent to the concept and mechanisms of pattern generation within the central nervous system. The key advantage would then be that the neuroscience community as a whole would gain appreciation of the fact that proprioceptive reflexes are not hard-wired but rather are context-and phase-dependent, with the central nervous system selecting input-output pathways appropriate for the task at hand.

Keywords

Central Pattern Generation Antagonistic Muscle Behavioural Brain Research Locomotor Rhythm Spinal Reflex 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Coghill, G. E., 1929Anatomy And The Problem of BehaviorHafner, New York, pp. 86–87.Google Scholar
  2. Bekoff, A., 1981, Embryonic development of the neural circuitry underlying motor coordination, in:Studies in Developmental Neurobiology—Essays in Honor of Viktor HamburgerW. Maxwell Cowan, ed., Oxford University Press, New York, pp. 134–170.Google Scholar
  3. Brown, T. G., and Sherrington, C. S., 1912, The rule of reflex response in the limb reflexes of the mammal and its exceptionsJournal of Physiology44, 125–130.PubMedGoogle Scholar
  4. Carpenter, C., and Ferguson, G. W., 1977, Variation and evolution of stereotyped behavior in reptiles, in:Biology of the Reptilia, vol. 7, Ecology and BehaviorC. Gans and D. W. Tinkle, eds., Academic Press, New York, pp. 335–403.Google Scholar
  5. Cazalets, J. R., Menard, I., Crémieux, J., and Clarac, F., 1990, Variability as a characteristic of immature motor systems: an electromyographic study of swimming in the newborn ratBehavioural Brain Research40, 215–225.PubMedCrossRefGoogle Scholar
  6. Duysens, J., Clarac, F., and Cruse, H., 2000, Load-regulating mechanisms in gait and posture: comparative aspectsPhysiological Reviews80, 83–133.PubMedGoogle Scholar
  7. Eccles, J. C., and Gibson, W. C., 1979Sherrington — His Life and ThoughtSpringer International, Berlin.CrossRefGoogle Scholar
  8. Emerson, S. B, and Koehl, M. A. R., 1990, The interaction of behavioral and morphological change in the evolution of a novel locomotor type: “flying” frogsEvolution44, 1931–1946.CrossRefGoogle Scholar
  9. Gatesy, S., and Dial, K.P., 1996, Locomotor modules and the evolution of avian flightEvolution50, 331–340. Grillner, S., 1975, Locomotion in vertebrates: Central mechanisms and reflex interactionPhysiological Reviews55, 247–304.Google Scholar
  10. Grillner, S., 1981, Control of locomotion in bipeds, tetrapods and fish, in:Handbook of Physiology sec. 1 vol. I1 pt. 2. The Nervous System: Motor Control(V. B. Brooks, vol. ed.), J. M. Brookhart and V. B. Mountcastle, eds., American Physiological Society, Bethesda, pp. 1179–1236.Google Scholar
  11. Grillner, S., Cangiano, L., Hu, G., Thompson, R., Hill, R., and Wallén, P., 2000, The intrinsic function of amotor system--from ion channels to networks and behaviorBrain Research886, 224–236.PubMedCrossRefGoogle Scholar
  12. Gurfinkel, V. S., Levik, Y. S., Kazzenikov, O. V., and Selionov, V. A., 1998, Locomotor-like movements evoked by leg muscle vibration in humansEuropean Journal of Neuroscience10, 1608–1612.PubMedCrossRefGoogle Scholar
  13. Harris-Warrick, R. M., and Marder, E., 1991, Modulation of neural networks for behaviorAnnual Reviews of Neuroscience14, 39–57.Google Scholar
  14. Hasan, Z., and Stuart, D. G., 1988, Animal solutions to problems of movement control: The role of proprioceptorsAnnual Reviews of Neuroscience 1 1199–223.CrossRefGoogle Scholar
  15. Herzog, E. D., and Tosini, G., 2001, The mammalian circadian clock shopSeminars in Cell and Developmental Biology12, 295–303.PubMedCrossRefGoogle Scholar
  16. Hore, J., Phillips, C. G., and Porter, R., 1973, The effects of pyramidotomy on motor performance in the brush-tailed possum (Trichosurus vulpecula)Brain Research49, 181–184.PubMedCrossRefGoogle Scholar
  17. Huang, A., Noga, B. R., Carr, P. A., Fedirchuk, B., and Jordan, L. M., 2000, Spinal cholinergic neurons activated during locomotion: localization and electrophysiological characterizationJournal of Neurophysiology83, 3537–3547.PubMedGoogle Scholar
  18. Hildebrand, J. G., and Shepherd, G. M., 1997, Mechanisms of olfactory discrimination: Common principles across phylaAnnual Reviews of Neuroscience20, 595–631.CrossRefGoogle Scholar
  19. Hultborn, H.. 2001, State-dependent modulation of sensory feedbackJournal of Physiology533, 5–13.PubMedCrossRefGoogle Scholar
  20. lwaniuk, A. N., Pellis, S. M., and Whishaw, I. Q., 1999, Is digital dexterity really related to corticospinal projections?: A re-analysis of the Heffner and Masterton data set using modern comparative statisticsBehavioural Brain Research101, 173–87.CrossRefGoogle Scholar
  21. Jankowska, E., 2001, Spinal interneuronal systems: identification, multifunctional character and reconfigurations in mammalsJournal of Physiology533, 31–40.PubMedCrossRefGoogle Scholar
  22. Jankowska, E., Jukes, M. G. M., Lund, S., and Lundberg, A., 1967, The effect of DOPA on the spinal cord. 5. Reciprocal organization of pathways transmitting excitatory action to alpha motoneurones of flexors and extensorsActa Physiologica Scandinavica70, 369–388.PubMedCrossRefGoogle Scholar
  23. Llinás, R., 2001I of the Vortex From Neurons to SelfMIT Press, Cambridge.Google Scholar
  24. Hinds, R., Hillman, D. E., and Precht, W., 1970, Functional aspects of cerebellar evolution, in:The Cerebellum in Health and Disease W.S. Fields and W. D. Willis, eds., Green, St. Louis, pp.269–291.Google Scholar
  25. Lundberg, A., 1969a, Convergence of excitatory and inhibitory action on interneurones in the spinal cord, in:The InterneuronM. A. B. Brazier, ed., University of California Press, Los Angeles, pp. 231–236.Google Scholar
  26. Lundberg, A., 1969bReflex Control of Stepping. The Nansen Memorial Lecture VUniversitetsforlaget, Oslo. McCrea, D. A., 2001, Spinal circuitry of sensorimotor control of locomotionJournal of Physiology533, 41–50.Google Scholar
  27. McDonagh, J. C., Callister, R. J., Brichta, A. M., Reinking, R. M., and Stuart, D. G.,1999, A commentary on the properties of spinal intemeurons vs. motoneurons in vertebrates, and their firing-rate behavior during movement, in:Motor Control Today and TomorrowG. Gantchev, ed., Academic Publishing House “Prof. M. Drinov,” Sofia, pp. 3–29.Google Scholar
  28. Magnus, R., 1909, On the control of movement by the central nervous system (in German)Pflügers Archiv European Journal of Physiology130, 219–269.CrossRefGoogle Scholar
  29. Matsuyama, K., and Mori, S., 1998, Lumbar intemeurons involved in the generation of fictive locomotion in catsAnnals of The New York Academy of Sciences860, 441–3.PubMedCrossRefGoogle Scholar
  30. Orlovsky, G. N., Deliagina, T. G., and Grillner, S., 1999Neuronal Control of Locomotion — From Mollusc to ManOxford University Press, New York.CrossRefGoogle Scholar
  31. Pearson, K. G., 1993, Common principles of motor control in vertebrates and invertebratesAnnual Reviews of Neuroscience16, 265–297.CrossRefGoogle Scholar
  32. Pearson, K., and Gordon, J., 2000, Spinal reflexes, in:Principles of Neuroscience4th ed., E. R. Kandel, J. H. Schwartz and T. M. Jessell, eds., McGraw-Hill, New York, pp. 713–36.Google Scholar
  33. Prochazka, A., 1996, Proprioceptive feedback and movement regulation, in:Handbook of Physiology sec. 12. Exercise: Regulation and Integration of Multiple SystemsL. B. Rowell and J. T. Shepherd, eds., Oxford University Press, New York, pp. 89–127.Google Scholar
  34. Prochazka, A., Clarac, F., Loeb, G. E., Rothwell, J. C., and Wolpaw, J. R., 2000, What do reflex and voluntary mean? Modern views on an ancient debateExperimental Brain Research 130417–32.CrossRefGoogle Scholar
  35. Richmond, F. J. R., Cornell, B. D., and Singh, K., 1999, Animal models of motor systems: cautionary tales from studies of head movementProgress in Brain Research123, 411–416.PubMedCrossRefGoogle Scholar
  36. Roberts, A., Soffe, S. R., Wolf, E. S., Yoshida, M., and Zhao, F. Y., 1998, Central circuits controlling locomotion in young tadpolesAnnals of the New York Academy of Sciences860, 19–34.PubMedCrossRefGoogle Scholar
  37. Rossignol, S., 1996, Neural control of stereotypic limb movements, in:Handbook of Physiology sec. 12. Exercise: Regulation and Integration of Multiple SystemsL. B. Rowell and J. T. Shepherd, eds., Oxford University Press, New York, pp. 173–216.Google Scholar
  38. Shepherd, G.M., 1994NeurobiologyOxford University Press, New York.Google Scholar
  39. Sherrington, C. S., 1900, On the innervation of antagonistic muscles. Sixth noteProceedings of the Royal Society of London67B, 66–67.Google Scholar
  40. Sherrington, C. S., 1905, On reciprocal innervation of antagonistic muscles. Seventh noteProceedings of the Royal Society of London76B, 160–163.CrossRefGoogle Scholar
  41. Sherrington, C. S., 1908a On the innervation of antagonistic muscles. Eleventh note: Further observations on successive inductionProceedings of the Royal Society of London80B, 53–71.CrossRefGoogle Scholar
  42. Sherrington, C. S., 1908b On reciprocal innervation of antagonistic muscles. Twelth note: Proprioceptive reflexesProceedings of the Royal Society of London80B, 552–564.CrossRefGoogle Scholar
  43. Sherrington, C. S., 1909, On plastic tonus and proprioceptive reflexesQuarterly Journal of Experimental Physiology2, 109–156.Google Scholar
  44. Sherrington, C. S., 1910, Flexion-reflex of the limb, crossed extension-reflex, and reflex stepping and standingJournal of Physiology40, 28–121.Google Scholar
  45. Sherrington, C. S., 1931, Quantitative management of contraction in lowest level co-ordination. Hughlings Jackson LectureBrain54, 1–28.CrossRefGoogle Scholar
  46. Sherrington, C. S., 1932, VII. Lower reflex co-ordination, in:Reflex Activity of the Spinal CordR.S. Creed, D. Denny-Brown, J. C. Eccles, E. G. T. Liddell and C. S. Sherrington, eds., Clarendon Press, Oxford, pp 104–159.Google Scholar
  47. Sherrington, C.S., and Sowton, S.C.M., 1911a, Chloroform and reversal of reflex effectJournal of Physiology42, 383–388.Google Scholar
  48. Sherrington, C.S., and Sowton, S.C.M., 1911b, Reversal of the reflex effect of an afferent nerve by altering the character of the electrical stimulus appliedProceedings of the Royal Society of London83B, 435–446.CrossRefGoogle Scholar
  49. Shik, M. L., Severin, F. V., and Orlovsky, G. N., 1966, Control of walking and running by means of electrical stimulation of the mid-brainBiophysics11, 756–765.Google Scholar
  50. Stein, P. S. G., 1995, A multi-level approach to motor pattern generation, in:Neural Control of Movement W.R. Ferrell and U. Proske, eds., Plenum Press, New York, pp. 159–165.CrossRefGoogle Scholar
  51. Stein, P. S. G., 1999, Central pattern generators and interphyletic awarenessProgress in Brain Research123, 259–271.PubMedCrossRefGoogle Scholar
  52. Stein, P. S. G., McCullough, M. L., and Currie, S. N., 1998, Spinal motor patterns in the turtleAnnals of The New York Academy of Sciences860, 142–154.PubMedCrossRefGoogle Scholar
  53. Stein, P. S. G., Grillner, S., Selveston, A. I., and Stuart, D. G., (eds.), 1997Neurons Networks and Motor BehaviorMIT Press, Boston.Google Scholar
  54. Strausfeld, N. J., Hansen, L., Li, Y., Gomez, R. S., and Ito. K., 1998, Evolution, discovery, and interpretations of arthropod mushroom bodiesLearning and Memory 5 11–37. PubMedGoogle Scholar
  55. Stuart, D. G., 1985, Summary and challenges for future work, in:Motor Control: From Movement Trajectories to Neural Mechanisms. Short Course SyllabusP.S.G. Stein, ed., Society for Neuroscience, Bethesda, pp. 95–105.Google Scholar
  56. Stuart, D. G., and McDonagh, J. C., 1998, Reflections on a Bernsteinian approach to systems neuroscience: The controlled locomotion of high-decerebrate cats, in:Progress in Motor Control: Bernstein’s Traditions in Movement StudiesM. L. Latash, ed., Human Kinetics, Champaign, pp. 21–49.Google Scholar
  57. Stuart, D. G., Pierce, P. A., Callister, R. J., Brichta, A., and McDonagh, J. C., 2001, Sir Charles Sherrington: humanist, mentor, and movement neuroscientist, in:Classical Papers in Movement ScienceM. L. Latash, and V. Zatsiorsky, eds., Human Kinetics, Champaign, pp. 317–374.Google Scholar
  58. von Uexkull, R. R., 1897, On conditions underlying the initiation of secondary movement (in German)Zeitschrift fur Biologie35, 183–191.Google Scholar
  59. von Uexkull, R. R., 1904a, Studies on posture II: movement of the brittle star (in German)Zeitschrift fur Biologie44, 1–37.Google Scholar
  60. von Uexkull, R. R., 1904b, The origin of rhythmicity in the animal kingdom (in German)Ergebnisse der Physiologie3, 1–11.CrossRefGoogle Scholar
  61. Ulinsky, P. S., 1997, Vertebrate nervous system, in:Comparative Physiology sec. 13 vol. IIW.H. Dantzler, cd., Oxford University Press, New York, pp. 17–53.Google Scholar
  62. Wiesendanger, M., 1999, Manual dexterity and the making of tools - an introduction from an evolutionary perspectiveExperimental Brain Research 1281–5.CrossRefGoogle Scholar
  63. Windhorst, U, 1996, Spinal cord and brainstem: pattern generators and reflexes, in:Comprehensive Human Physiology: From Cellular Mechanisms to Integration vol. 1R. Greger and U. Windhorst, eds., Springer, Berlin, pp.1007–1032.Google Scholar

Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Douglas G. Stuart
    • 1
  1. 1.Department of PhysiologyThe University of Arizona College of MedicineTucsonUSA

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