Abstract
Labyrinthine afferents respond to both angular velocity (semicircular canals) and linear acceleration (otoliths), including gravity. Given their response to gravity, the otoliths are likely to have an important role in the postural functions of the vestibular apparatus. Unilateral vestibular ablation has dramatic effects on posture in many animals, but less so in primates. Nevertheless, bilateral vestibular lesions lead to disabling symptoms in man related to disturbed ocular and postural control and impaired perception of slopes and accelerations. While seimicircular canal function can be assessed through its effects on vestibular ocular reflexes, assessment of otolith function in man has traditionally been much more difficult. Recent definition of a short latency vestibulocollic reflex, activated by sound and appearing to arise from the saccule, shows promise as a new method of noninvasive assessment of otolith function.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Brodai A., 1981, Neurological Anatomy, 3rd ed., Oxford University Press, New York, pp. 470–488.
Cairns, H., and Brain, W. R., 1933, Aural vertigo: treatment by division of the eighth nerve. Lancet i 946–952.
Camis, M., 1930, The Physiology of the Vestibular Apparatus, Translated by Creed, R.S., Oxford University Press, Oxford, pp. 47–68.
Colebatch, J. G., Halmagyi, G. M., and Skuse, N. F., 1994, Myogenic potentials generated by a click-evoked vestibulocollic reflex, Journal of Neurology, Neurosurgery and Psychiatry, 57, 190–197.
Colebatch, J. G. and Rothwell, J. C., 1993, Vestibular-evoked EMG responses in human neck muscles, Journal of Physiology, 473, 18P.
Cremer, P. D., Halmagyi, G. M., Aw, S. T., Curthoys, I. S., McGarvie, L. A., Todd, M. J., Black, R. A., and Hannigan, I. P., 1998, Semicircular canal plane head impulses detect absent function of individual semicircular canals, Brain, 121, 699–716.
Dow, R. S., 1938, The effects of unilateral and bilateral labyrinthectomy in monkey, baboon and chimpanzee, American Journal of Physiology, 121, 392–399.
Fernandez C., Goldberg J. M., and Abend, W. K., 1972, Responses to static tilts of peripheral neurons innervating otolith organs of the squirrel monkey, Journal of Neurophysiology, 35, 978–997.
Fetter, M., 2000, Assessing vestibular function: which tests, when? Experimental Brain Research, 247, 335–342.
Gresty, M., 1987, Stability of the head: studies in normal subjects and in patients with labyrinthine disease, head tremor, and dystonia, Movement Disorders, 2, 165–185.
Guitton, D, Kearney, R. E., Werely, N., and Peterson, B. W., 1986, Visual, vestibular and voluntary contributions to human head stabilisation, Experimental Brain Research, 64, 59–69.
Halmagyi, G. M., and Colebatch, J. G., 1995, Vestibular evoked myogenic potentials in the stemomastoid muscle are not of lateral canal origin, Acta Oto-Laryngologica, Supplement, 520, 1–3.
Halmagyi, G. M., and Curthoys, I. S., 1988, A clinical sign of canal paresis, Archives of Neurology, 45, 737–739.
Halmagyi, G. M., and Curthoys, 1. S., 1999, Clinical testing of otolith function, Annals of the New York Academy of Sciences, 871, 195–204.
Halmagyi, G. M., Curthoys, I. S., and Dai, M. J., 1990, Diagnosis of unilateral otolith hypofunction, Neurologic Clinics, 8, 313–329.
Halmagyi G. M., Yavor R. A., and Colebatch J. G., 1995, Tapping the head activates the vestibular system: a new use for the clinical tendon hammer, Neurology, 45, 1927–1929.
Less, K., 1996, Vestibulotoxic drugs and other causes of acquired bilateral peripheral vestibulopathy, in: Disorders of the Vestibular System, R.W. Baloh, G.M. Halmagyi, eds., Oxford University Press, New York, pp. 360–373.
J.C., 1952, Living without a balancing mechanism, New England Journal of Medicine, 246, 458–460.
Kushiro, K., Zakir, M., Ogawa, Y., Sato, H., and Uchino, Y., 1999, Saccular and utricular inputs to stemocleidomasotid motoneurons of decerebrate cats, Experimental Brain Research, 126, 410–416.
Magnus, R., 1926, Some results of studies on the physiology of posture, Lancet ii: 531–536, 585–588.
Martin, J.P., 1967, The Basal Ganglia and Posture, Pitman, London, pp. 36–51.
McCue, M. P., and Guinan, J. J. Jnr, 1995, Spontaneous activity and frequency selectivity of acoustically responsive vestibular afferents in the cat, Journal of Neurophysiology, 74, 1563–1572.
Melvill Jones G., and Watt, D. G. D., 1971, Muscular control of landing from unexpected falls in man, Journal of Physiology, 219, 729–737.
Murofushi, T., Curthoys, I. S., Topple, A. N., Colebatch, J. G., and Halmagyi, G. M., 1995, Responses of guinea pig primary vestibular neurons to clicks, Experimental Brain Research, 103, 174–178.
Prochazka, A., Proprioceptive feedback and movement regulation, in: Exercise: Regulation and Integration of Multiple Systems, Handbook of Physiology, Section 12, L.B. Rowell, J.T. Shepherd, eds, Oxford University Press, New York, pp. 89–217.
Roberts, T. D. M., 1995, Understanding Balance, Chapman & Hall, London, pp. 94–174.
Sherrington, C. S., 1947, The Integrative Action of the Nervous System, 2nd ed., Yale University Press, New Haven, pp. 335–344.
Suzuki, J. I., and Cohen, B., 1964, Head, eye, body and limb movements from semicircular canal nerves, Experimental Brain Research, 10, 393–405.
Uchino, Y., Sato, H., Sasaki, M., Imagawa, M., Ikegami, H., Isu, N., and Graf, W., 1997, Sacculocollic reflex arcs in cats, Journal of Neurophysiology, 77, 3003–3012.
Watson, S. R. D., and Colebatch, J. G., 1998, Vestibulocollic reflexes evoked by galvanic stimulation in man, Journal of Physiology, 513, 587–597.
Watt, D. G. D., 1976, Responses of cats to sudden falls: an otolith-originating reflex assisting landing, Journal of Neurophysiology, 39, 257–265.
Welgampola, M. S., and Colebatch, J. G., 2001, Vestibulospinal reflexes: quantitative effects of sensory feedback and postural task, Experimental Brain Research, 139, 345–353.
Wilson, V. J., and Peterson, B. W., 1978, Peripheral and central substrates of vestibulospinal reflexes, Physiological Reviews, 58, 80–105.
Wilson, V.J., and Schor, R.H., 1999, The neural substrate of the vestibulocollic reflex: what needs to be learned, Experimental Brain Research, 129, 483–493.
Wilson, V.J., and Yoshida, M., 1969, Comparison of effects of stimulation of Deiter’s nucleus and medial longitudinal fasciculus on neck, neck, forelimb, and hindlimb motoneurons, Journal of Neurophysiology, 32, 743–758.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Springer Science+Business Media New York
About this chapter
Cite this chapter
Colebatch, J.G. (2002). Consequences and Assessment of Human Vestibular Failure. In: Gandevia, S.C., Proske, U., Stuart, D.G. (eds) Sensorimotor Control of Movement and Posture. Advances in Experimental Medicine and Biology, vol 508. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0713-0_13
Download citation
DOI: https://doi.org/10.1007/978-1-4615-0713-0_13
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-5206-8
Online ISBN: 978-1-4615-0713-0
eBook Packages: Springer Book Archive