Abstract
DNA content detected by video-imaging and flow cytometry in malignant and premalignant cells becomes more and more often routine adjunct to clinical and histological diagnosis. It seems that the presence of abnormal DNA in many neoplasms is correlated with the poor clinical course (1,4,5). However, diploid cell population was found also in such malignant cell transformations as leukemia, lymphoma, and aneuploidy in such benign transformations as thyroid adenoma, mastopathy and premalignant cutaneous lesions. It is clear that DNA ploidy is not always an adequate parameter to differentiate benign from malignant lesions.
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© 2001 Springer Science+Business Media New York
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Skowronek, J., Karas, Z., Krenz, R.M., Warchoł, J.B. (2001). Flow and video-imaging cytometry — usefulness of DNA ploidy measurements in diagnosis of malignant melanoma. In: Mackiewicz, A., Kurpisz, M., Żeromski, J. (eds) Progress in Basic and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 495. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0685-0_63
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DOI: https://doi.org/10.1007/978-1-4615-0685-0_63
Publisher Name: Springer, Boston, MA
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