Heterogeneity of Major Urinary Proteins in House Mice: Population and Sex Differences
House mice (Mus domesticus) and rats (Rattus norvegicus) secrete large quantities of protein into their urine as the normal condition (Finlayson and Baumann, 1958). These proteins are major urinary proteins (MUP) and alpha2u-globulins respectively. Both are small proteins that have been assigned to the lipocalin protein family on the basis of sequence data (reviewed by Flower, 1996) and X-ray crystallography (Bocskei et al., 1992). As such, both display a typical lipocalin beta-barrel structure enclosing an internal cavity in which volatile ligands may bind.
KeywordsGlycerol Maize Albumin Creatinine Electrophoresis
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