Abstract
In addition to its putative role in parturition and lactation, the neuropeptide oxytocin (OXT), exerts a myriad of appended actions within the central nervous system (Argiolas and Gessa, 1991). In the present report we focus upon the capacity for OXT to enhance memory/recognition responses. The beneficial effects of OXT upon memory/recognition have been demonstrated in a variety of paradigms (Engelmann et al., 1996). Since many of these paradigms consist of tests involving social recognition, which rely heavily upon olfaction (Sawyer et al., 1984; Dantzer et al., 1990), we were interested in the extent to which the olfactory bulb (OB) was involved with mediating these recognition responses. Accordingly, we addressed two fundamental questions which comprised the basis for this report: 1) Will OXT affect social recognition when applied within the OB? and 2) How does this neuropeptide function at this site? In an attempt to answer these questions, we combined a behavioral assay of social recognition with infusions/measurements of agents within the OB to evaluate whether the localized application of neuromodulators at this site would alter social recognition.
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Dluzen, D.E., Shang, Y., Landgraf, R. (2001). Oxytocin, Norepinephrine and Olfactory Bulb Mediated Recognition. In: Marchlewska-Koj, A., Lepri, J.J., Müller-Schwarze, D. (eds) Chemical Signals in Vertebrates 9. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0671-3_14
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