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Adducts of the Chloroform Metabolite Phosgene

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Biological Reactive Intermediates VI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 500))

Abstract

Chlorination of water for human consumption is important for disease prevention. However, halogenated by-products, such as trihalomethanes (THM), can be formed during this process (Bunn et al 1975). THM production raises public health concerns related to potential human cancer risk (Fawell, 2000). Chloroform (trichloromethane: TCM) is a byproduct that is frequently detected at relatively high concentrations (IARC, 1991), i.e. 0.1 to 300 μg/litre in finished drinking water (Uden and Miller, 1983) and up to 1 mg/litre in chlorinated swimming pool water (Lahl et al 1981).

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© 2001 Springer Science+Business Media New York

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Fabrizi, L., Taylor, G.W., Edwards, R.J., Boobis, A.R. (2001). Adducts of the Chloroform Metabolite Phosgene. In: Dansette, P.M., et al. Biological Reactive Intermediates VI. Advances in Experimental Medicine and Biology, vol 500. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0667-6_15

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  • DOI: https://doi.org/10.1007/978-1-4615-0667-6_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5185-6

  • Online ISBN: 978-1-4615-0667-6

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