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Gonadal Differentiation — Normal and Abnormal Testicular Development

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Pediatric Gender Assignment

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 511))

Abstract

This chapter concerning normal and abnormal testicular development represents 28 years of our experience based on semi-thin histologic sections of over 13,000 testicular biopsies mostly from patients with cryptorchidism and male infertility. The series also includes testicular biopsies from 30 testes of complete Androgen Insensitivity Syndrome (AIS), 20 of mixed gonadal dysgenesis, 24 of XXY Klinefelter syndrome, 6 of male Turner syndrome (Noonan syndrome), 10 of XX-male syndrome, and 10 of hernia uteri inguinalis (persistent Mullerian duct syndrome). Special effort was taken to compare abnormal testicular development from intersex patients with that of normal testicular development from birth to adulthood.

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Hadziselimovic, F., Huff, D. (2002). Gonadal Differentiation — Normal and Abnormal Testicular Development. In: Zderic, S.A., Canning, D.A., Carr, M.C., Snyder, H.M. (eds) Pediatric Gender Assignment. Advances in Experimental Medicine and Biology, vol 511. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0621-8_2

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  • DOI: https://doi.org/10.1007/978-1-4615-0621-8_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5162-7

  • Online ISBN: 978-1-4615-0621-8

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