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Synthesis of Poly (Carboxyphenoxypropane-Sebacic Anhydride) for the Delivery of Drugs to the Brain

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Blood—Brain Barrier

Abstract

Bioerodible polymeric implants have been used for the delivery of a range of anticancer drugs [1–5]. These devices are favorable for clinical use because the device is eliminated from the brain after the drug has been depleted. Most studies have been conducted by Brem and co-workers using poly(l,3-p-carboxyphenoxypropane-sebacic acid) [P(CPP-SA)] as drug carrier [4–11].

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Domb, A.J., Kubek, M. (2001). Synthesis of Poly (Carboxyphenoxypropane-Sebacic Anhydride) for the Delivery of Drugs to the Brain. In: Kobiler, D., Lustig, S., Shapira, S. (eds) Blood—Brain Barrier. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0579-2_27

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  • DOI: https://doi.org/10.1007/978-1-4615-0579-2_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5141-2

  • Online ISBN: 978-1-4615-0579-2

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