Physiology of the Exocrine Pancreas

  • John M. Howard
  • Walter Hess


Johann Conrad Brunner (1653–1727) (Figure 2.1), whom history would record as the first to resect a pancreas, was born in Diessenhofen, a small rural town in the Swiss canton of Thurgovia, on January 13, 1653, 11 years after Wirsüng’s discovery, and nine years after the birth of de Graaf. Like so many of the pancreatic pioneers, he studied medicine in Strasbourg, from 1669 to 1672, subsequently making extensive travels to the medical centers in Paris, London, Oxford, Amsterdam, and Leiden, before returning to Strasbourg where he graduated in 1675, aged 22.


Pancreatic Duct Conditioned Reflex Nobel Prize Pancreatic Fistula Pancreatic Juice 
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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • John M. Howard
    • 1
  • Walter Hess
    • 2
  1. 1.Emeritus Medical College of OhioToledoUSA
  2. 2.University of BaselSwitzerland

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