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Acute Lung Injury and Pneumonia in Mice

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Book cover The Physiological Genomics of the Critically Ill Mouse

Part of the book series: Basic Science for the Cardiologist ((BASC,volume 16))

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Abstract

Comparable inflammatory processes are activated during the acute respiratory distress syndrome (ARDS) and pneumonia. Although required in most patients with ARDS and patients with severe pneumonia, mechanical ventilation is potentially harmful because it may cause local inflammation by itself (so-called ventilator-induced lung injury, VILI). Interestingly, VILI involves the same inflammatory mechanisms as for ARDS and pneumonia.

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Authors and Affiliations

  1. Dept. of Intensive Care Medicine, Laboratory of Experimental Internal Medicine, the Netherlands

    Marcus J. Schultz

  2. Laboratory of Experimental Internal Medicine, the Netherlands

    Marcus J. Schultz & Tom van der Poll

  3. Dept. of Infectious Diseases, Tropical Medicine and AIDS Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands

    Tom van der Poll

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  1. Marcus J. Schultz
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  2. Tom van der Poll
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  1. Department of Physiology Academic Medical Center, University of Amsterdam, The Netherlands

    Can Ince

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Schultz, M.J., van der Poll, T. (2004). Acute Lung Injury and Pneumonia in Mice. In: Ince, C. (eds) The Physiological Genomics of the Critically Ill Mouse. Basic Science for the Cardiologist, vol 16. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0483-2_20

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  • DOI: https://doi.org/10.1007/978-1-4615-0483-2_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5099-6

  • Online ISBN: 978-1-4615-0483-2

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