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Sleep breathing abnormalities in neuromuscular diseases

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Sleep

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Abstract

In neuromuscular diseases, respiratory muscle paralysis, and the thoracic deformities which often accompany these diseases, may lead to a respiratory deficiency resulting in alveolar hypoventilation [8, 16, 21, 23, 46]. During sleep, these breathing abnormalities may worsen and apnoeas or hypopnoeas may appear. Thus patients with moderate ventilatory function restrictions may present episodes of severe haemoglobin desaturation, during sleep. These patients also complain of nocturnal arousals with a sensation of asphyxia, as well as daytime sleepiness. Nocturnal mechanical ventilation will correct nocturnal alveolar hypoventilation, improve sleep quality and daytime haematosis [16, 19, 20, 26, 36, 38, 48]. It is thus important to detect sleep breathing abnormalities by polysomnographic recording in subjects presenting symptoms suggesting sleep breathing abnormalities [1].

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  1. Service de Réanimation Médicale et Explorations Fonctionnelles, Hôpital Raymond Poincaré, Garches, France

    M. A. Quera Salva, G. Mroue, Ph. Gajdos, J. C Raphael & F. Lofaso

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  1. Hôpital Gui de Chauliac, Montpellier, France

    Michel Billiard

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Salva, M.A.Q., Mroue, G., Gajdos, P., Raphael, J.C., Lofaso, F. (2003). Sleep breathing abnormalities in neuromuscular diseases. In: Billiard, M. (eds) Sleep. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0217-3_46

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  • DOI: https://doi.org/10.1007/978-1-4615-0217-3_46

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