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Physiological Oxygen Measurements Using Oxygen Electrodes

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Oxygen Transport To Tissue XXIII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 510))

Abstract

It was the development by Clark in 1956 of the membrane-covered “integral” electrode that opened the field for truly physiological in vivo - and indeed clinical - measurements of oxygen partial pressure in blood and tissue. Since then, much of our knowledge about oxygen transport to tissue has been gained by the use of polarographic oxygen (and hydrogen) electrodes — many of them of the Clark-type. It is not possible in this paper to examine all of these applications and the reader is referred to a comprehensive review by Ltibbers.

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References

  1. L. C. Clark, Monitoring and control of blood and tissue oxygen, Trans. Am. Soc. Artif Intern. Organs 2:4148 (1956).

    Google Scholar 

  2. D. W. Lubbers, Oxygen electrodes and optodes and their application in vivo, Adv. Exp. Med. Biol. 388:13-34 (1996).

    Article  Google Scholar 

  3. R. Huch, D. W. Lubbers and A. Huch, in: Oxygen Measurements in Medicine and Biology, edited by J. P. Payne and D. W. Hill (Butterworths, London, 1975) pp. 121–138.

    Google Scholar 

  4. R. Carter and S. Banham, Use of transcutaneous oxygen and carbon dioxide tensions for assessing indices of gas exchange during exercise testing, Resp. Med. 94:350–355 (2000).

    Article  CAS  Google Scholar 

  5. M. Mars, A. McKune and J. V. Robbs, A comparison of laser Doppler fluxmetry and transcutaneous oxygen pressure measurement in the dysvascular patient requiring amputation, Eur. J. Vasc. Endovasc. Surg.. 16:53–58 (1998).

    Article  PubMed  CAS  Google Scholar 

  6. H. Baumgärtl, W. Zimelka and D. Lubbers, Evaluation of p02 profiles to describe the oxygen pressure field within the tissue, Comp. Biochem. Physiol. (In Press).

    Google Scholar 

  7. P. Vaupel, K. Schlenger, C. Knoop and M. Hockel, Oxygenation in human tumors: Evaluation of tissue oxygen distribution in breast cancers by computerized 02 tension measurement, Cancer Res., 51:3316–3322 (1991).

    PubMed  CAS  Google Scholar 

  8. M. Kessler and D. W. Lubbers, Aufbau und Anwendungsmöglichkeiten verschiedener P02-Elektroden, Pfug. Arch. ges. Physiol. 291:R82 (1966).

    Google Scholar 

  9. M. Kessler, D. K. Harrison and J. Höper, in: Microcirculatory Technology, edited by C. H. Baker and W. F. Nastuk (Academic Press, New York, 1986) pp. 391–425.

    Google Scholar 

  10. D. K. Harrison, Catchment depths of surface electrodes for H2 and 02 in tissue, Adv. Exp. Med. Biol. 411:551–6 (1997).

    Article  PubMed  CAS  Google Scholar 

  11. M. Kessler, J. Höper, D. K. Harrison, K. Skolasinska, W. P. Klövekom, F. Sebening, H. J. Volkholz, I. Beir, C. Kernbach, V. Rettig and H. Richter, Tissue 02 supply under normal and pathological conditions, Adv. Exp. Med. Biol. 169:69–80 (1984).

    Article  PubMed  CAS  Google Scholar 

  12. D. K. Harrison, M. Kessler and S. K. Knauf, Regulation of capillary blood flow and oxygen supply in skeletal muscle in dogs during hypoxaemia, J Physiol. (Lond.) 420: 431–446 (1989).

    Google Scholar 

  13. D. K. Harrison, M. Kessler, S. Birkenhake and S. K Knauf, Local oxygen supply and blood flow regulation in contracting muscle in dogs and rabbits../. Physiol. (Lond.) 422:227–243 (1990).

    CAS  Google Scholar 

  14. D. K. Harrison, P. T. McCollum, D. J. Newton, P. Hickman and A. S. Jain, Amputation level assessment using lightguide spectrophotometry, Prosthet. Orthot. Int. 19:139–147 (1995).

    PubMed  CAS  Google Scholar 

  15. P. T. McCollum, V. A. Spence and W. F. Walker, Amputation for peripheral vascular disease: the case for level selection, Br. J Surg. 75:1193-1195 (1988).

    Article  PubMed  CAS  Google Scholar 

  16. H. Baumgartl, A. M. Ehrly, K. Saeger-Lorenz and D. Lubbers, in: Clinical Oxygen Pressure Measurement, edited by A. M. Ehrly, J. Hauss and R. Huch (Springer-Verlag, Berlin, 1987), pp. 121–128.

    Chapter  Google Scholar 

  17. W. Wang, C. P. Winlove and C. C. Michel, Distribution of oxygen partial pressure (PO2) in dermal papillae of human finger nailfolds,J Vasc. Res. 38:399 (2001).

    Google Scholar 

  18. G. Holst, T. Köster, E. Voges andD. W. Lubbers, FLOX - an oxygen-flux-measuring system using a phase-modulation method to evaluate the oxygen-dependent fluorescence lifetime, Sens. and Actuators B 29:231–239 (1995).

    Article  Google Scholar 

  19. M. Stucker, P. Altmeyer, A. Struk, K. Hoffmann, L. Schulze, A. Röchling and D. W. Lubbers, The transepidermal oxygen flux from the environmert is in balance with the capillary oxygen supply, J. Invest. Dermatol. 114:533-540 (2000).

    Article  PubMed  CAS  Google Scholar 

  20. M. Stucker, A. Struk, P. Altmeyer, M. Herde, H. Baumgartl and D. W. Lubbers, The cutaneous uptake of atmospheric oxygen contributes significantly to the oxygen supply of human epidermis, J. Physiol. (Lond.) 538: 985–994 (2002).

    Article  CAS  Google Scholar 

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Harrison, D.K. (2003). Physiological Oxygen Measurements Using Oxygen Electrodes. In: Wilson, D.F., Evans, S.M., Biaglow, J., Pastuszko, A. (eds) Oxygen Transport To Tissue XXIII. Advances in Experimental Medicine and Biology, vol 510. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0205-0_27

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  • DOI: https://doi.org/10.1007/978-1-4615-0205-0_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4964-8

  • Online ISBN: 978-1-4615-0205-0

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