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Analysis of the Transcriptional Regulation of Mouse Prostacyclin Synthase Gene

  • Susumu Ohkawara
  • Chieko Yokoyama
  • Manabu Shimonishi
  • Tadashi Tanabe
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 507)

Abstract

Prostacyclin (PGI2) is a powerful vasodilator and inhibits the platelet aggregation and the abnormal growth of smooth muscle cells.’ It is therefore considered to play a key role in vasoprotection and its decrease causes vascular disease such as atherosclerosis, pulmonary hypertension and myocardial infarction.

Keywords

Nuclear Extract Translational Start Site Bovine Aortic Endothelial Cell Unlabeled Probe Basal Promoter Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Susumu Ohkawara
    • 1
  • Chieko Yokoyama
    • 1
  • Manabu Shimonishi
    • 1
  • Tadashi Tanabe
    • 1
  1. 1.Department of PharmacologyNational Cardiovascular Center Research InstituteOsakaJapan

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