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Catalytic Properties of Purified Recombinant Anandamide Amidohydrolase

  • Natsuo Ueda
  • Kazuhisa Katayama
  • Sravan Kumar Goparaju
  • Yuko Kurahashi
  • Kenji Yamanaka
  • Hiroshi Suzuki
  • Shozo Yamamoto
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 507)

Abstract

The major degradative pathway of anandamide, an endogenous ligand for cannabinoid receptors, is its enzymatic hydrolysis to arachidonic acid and ethanolamine.1The enzyme responsible for this reaction has been referred to as anandamide amidohydrolase23or fatty acid amide hydrolase.4‘N-Acylethanolamine amidohydrolase’ reported much earlier by Schmid and co-workers5is probably identical to this enzyme.

Keywords

Arachidonic Acid Fatty Acid Amide Hydrolase Porcine Brain Resin Column Chromatography Relative Hydrolysis Rate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Natsuo Ueda
    • 1
  • Kazuhisa Katayama
    • 2
  • Sravan Kumar Goparaju
    • 1
  • Yuko Kurahashi
    • 1
  • Kenji Yamanaka
    • 1
  • Hiroshi Suzuki
    • 1
  • Shozo Yamamoto
    • 1
  1. 1.Department of BiochemistryTokushima University School of MedicineTokushimaJapan
  2. 2.Department of Cardiovascular SurgeryTokushima University School of MedicineTokushimaJapan

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