Abstract
In this preliminary report we present data showing that leukotrienes increase the baseline cell viability in human intestinal epithelial cells and that LTB4partially reverses the morphological hallmarks of non-necrotic cell death induced by the COX-2 specific inhibitor NS-398. The proposed signaling mechanisms regulating these events are summarized. Please view the work on LT signal transduction in these cells by Thodeti et al. in this volume.
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Öhd, J.F., Wikström, K., Sjölander, A. (2002). Do Leukotrienes Increase Cell Viability in Human Intestinal Epithelial Cells?. In: Honn, K.V., Marnett, L.J., Nigam, S., Dennis, E., Serhan, C. (eds) Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury, 5. Advances in Experimental Medicine and Biology, vol 507. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0193-0_30
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DOI: https://doi.org/10.1007/978-1-4615-0193-0_30
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