Manganese Lipoxygenase Has A Mononuclear Redox Center

  • Chao Su
  • Margareta Sahlin
  • Ernst H. Oliw
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 507)


Lipoxygenases catalyze dioxygenation on cis, cis—1,4-pentadiene moieties of fatty acids to cis-trans conjugated hydroperoxydienes. They are widely distributed in plants and animals (1, 2). All sequenced lipoxygenases belong to the same gene family. A characteristic feature is a non-heme metal center, which contains iron (1,2). One lipoxygenase with Mn as prosthetic metal (Mn-LO) has been discovered in the fungus Geaumannomyces graminis (3-6).


Linoleic Acid Hyperfine Splitting Accelerate Phase Octadecadienoic Acid Kinetic Trace 
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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Chao Su
    • 1
  • Margareta Sahlin
    • 2
  • Ernst H. Oliw
    • 1
  1. 1.Department of Pharmaceutical BiosciencesUppsala Biomedical Centre, Uppsala UniversityUppsalaSweden
  2. 2.Department of Molecular BiologyStockholm UniversityStockholmSweden

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