Taurine 5 pp 537-545 | Cite as

Taurine in Aging and Models of Neurodegeneration

  • Ralph DawsonJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 526)

Abstract

Taurine, the second most abundant amino acid in the CNS, is acknowledged to be important in cell volume regulation yet little is known about how aging might alter taurine homeostasis. Unfortunately, few investigators have focused on the study of taurine in aging and senescence. Previously we summarized much of the older work showing that taurine content declines in a number of tissues with advanced age in rodents1. I will briefly summarize some recent studies that have examined the effects of aging on taurine. I will also summarize our own findings that point to several potential mechanisms that may impact taurine homeostasis with advanced aging.

Keywords

Cholesterol Toxicity Attenuation Glutathione Ozone 

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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Ralph DawsonJr.
    • 1
  1. 1.Department of PharmacodynamicsCollege of Pharmacy, University of FloridaGainesvilleUSA

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