Abstract
In this study, we tried to continuously measure muscle oxygen consumption (m-VO2) by near infrared spectroscopy (NIRS) without arterial occlusions. We used an intermittent isometric exercise at high intensity, which elicits a spontaneous occlusion of the blood flow to the muscle due to an increase in intramuscular pressure. Changes in muscle oxygenation and phosphocreatine (PCr) concentration were monitored in 5 subjects during an intermittent isometric exercise (5 sec. contraction/5 sec. relaxation) at 50% of maximum voluntary contraction for 3 minutes. The rate of deoxygenation was measured from the 2nd sec. to the 3rd sec. of each muscle contraction. The rate of deoxygenation at the onset of exercise followed an exponential time course with a time constant of 42.0 ± 12.5 sec. (mean±SD). This value agreed with the time constant of the decrease in PCr (48.2 ± 10.2 sec.). This result suggests that m-VO2 was successfully monitored with a time resolution of 10 sec. by NIRS during exercise without arterial occlusion.
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References
Cheatle TR, Potter LA, Cope M, Delpy DT, Coleridge Smith PD, Scurr JH. Near-infrared spectroscopy in peripheral vascular disease. Br J Surg 1991;78:405–408.
De Blasi RA, Cope M, Ferrari M. Oxygen consumption of human skeletal muscle by near Infrared spectroscopy during tourniquet-induced ischemia in maximal voluntary contraction. Adv Exp Med Biol 1992;317: 771–777.
Hamaoka T, Lwane H, Shimomitsu T, Katsumura T, Murase N, Nishio S, Osada T, Kurosawa Y, Chance B. Noninvasive measures of oxidative metabolism on working human muscles by near infrared spectroscopy. J Appl Physiol 1996;81(3): 1410–1417.
Shiga T, Yamamoto K, Tanabe K, Nakase Y, Chance B. Study of an algorithm based on model experiments and diffusion theory for a portable tissue oximeter. J Biomed Opt 1997;2(2):154–161.
Chance B, Dait TM, Chang C, Hamaoka T, Hagerman F. Recovery from exercise induced desaturation in the quadriceps muscle of elite competitive rowers. Am J Physiol 1992;262:766–775.
Shiga T, Tanabe K, Nakase Y, Shida T, Chance B. Development of portable tissue oximeter using near infra-red spectroscopy. Med Biol Eng Comput 1995;33: 622–626.
Chance B, Nioka S, Kent J, McCully KK, Fountain M, Greenfeld R, Holtom G. Time resolved spectroscopy of hemoglobin and myoglobin in resting and ischemic muscle. Anal Biochem 1988;174:698–707.
Kushmerick MJ and Meyer RA. Chemical changes in rat leg muscle by phosphorus nuclear magnetic resonance. Am J Physiol 1985;248:542–549.
Meyer RA. A linear model of muscle respiration explains monoexponential phosphocreatine changes. Am J Physiol 1988;254:548–553.
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Hamaoka, T. et al. (2003). Muscle Oxygen Consumption at Onset of Exercise by Near Infrared Spectroscopy in Humans. In: Dunn, J.F., Swartz, H.M. (eds) Oxygen Transport to Tissue XXIV. Advances in Experimental Medicine and Biology, vol 530. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0075-9_45
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DOI: https://doi.org/10.1007/978-1-4615-0075-9_45
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