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Metabolic Modulation of Visual Sensitivity

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Retinal Degenerations

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 533))

Abstract

Vision is an energy demanding process. Changes in metabolic levels can affect how we see. The earliest evidence for the metabolic modulation of human vision dates back to the pioneering days of aviation when pilots reported darkened visual fields while flying at high altitudes without oxygen masks (McFarland and Evans,1939). Studies at sea level showed that lowering the partial pressure of oxygen decreased visual sensitivity (McFarland and Forbes, 1940) and ingesting glucose reversed the effects of hypoxia (McFarland et al, 1945). Lowering blood glucose under normal oxygen conditions can decrease sensitivity (McCrimmon et al, 1998).

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Author information

Authors and Affiliations

  1. Center for Vision Research, Department of Ophthalmology, Upstate Medical University, 750 East Adams Street, Syracuse, NY, 13210, USA

    Robert B. Barlow

  2. lnstitute for Sensory Research, Syracuse University, Syracuse, NY, USA

    Bart Farell

  3. Department of Medicine, Upstate Medical University, Syracuse, NY, 13210, USA

    Mukhtar Khan

Authors
  1. Robert B. Barlow
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  2. Bart Farell
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  3. Mukhtar Khan
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Editor information

Editors and Affiliations

  1. Beckman Vision Center, University of California, San Francisco, California, USA

    Matthew M. LaVail

  2. Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Joe G. Hollyfield

  3. Dean A. McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

    Robert E. Anderson

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© 2003 Springer Science+Business Media New York

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Barlow, R.B., Farell, B., Khan, M. (2003). Metabolic Modulation of Visual Sensitivity. In: LaVail, M.M., Hollyfield, J.G., Anderson, R.E. (eds) Retinal Degenerations. Advances in Experimental Medicine and Biology, vol 533. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0067-4_32

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  • DOI: https://doi.org/10.1007/978-1-4615-0067-4_32

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4909-9

  • Online ISBN: 978-1-4615-0067-4

  • eBook Packages: Springer Book Archive

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