Abstract
Recessive mutations in human myosin VIIa(MYO7A)cause either nonsyndromic deafness or, in most cases, Usher syndrome 1B (USH1B), which includes retinitis pigmentosa as well as deafness (Liu et al., 1997a; Liu et al., 1997b; Weil et al., 1995). Mutations in myosin VIIa have also been reported in shakerl mice (Gibson et al., 1995) and zebrafish (Ernest et al., 2000). However, retinal degeneration has not been observed in any of the mutant mice or zebrafish. In this respect, ten different alleles of shakerl mice have
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Slatter, T., Azarian, S.M., Tebbutt, S., Maw, M., Williams, D.S. (2003). Screen for Usher Syndrome 1b Mutations in the Ovine Myosin VIIa Gene. In: LaVail, M.M., Hollyfield, J.G., Anderson, R.E. (eds) Retinal Degenerations. Advances in Experimental Medicine and Biology, vol 533. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0067-4_19
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DOI: https://doi.org/10.1007/978-1-4615-0067-4_19
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